Literature DB >> 8454491

Measured dose to ovaries and testes from Hodgkin's fields and determination of genetically significant dose.

A Niroomand-Rad1, R Cumberlin.   

Abstract

PURPOSE: To determine the genetically significant dose from therapeutic radiation exposure with Hodgkin's fields by estimating the doses to ovaries and testes.
MATERIALS AND METHODS: Phantom measurements were performed to verify estimated doses to ovaries and testes from Hodgkin's fields. Thermoluminescent LiF dosimeters (TLD-100) of 1 x 3 x 3 mm3 dimensions were embedded in phantoms and exposed to standard mantle and paraaortic fields using Co-60, 4 MV, 6 MV, and 10 MV photon beams.
RESULTS: Our results show that measured doses to ovaries and testes are about two to five times higher than the corresponding graphically estimated doses for Co-60 and 4 MVX photon beams as depicted in ICRP publication 44. In addition, the measured doses to ovaries and testes are about 30% to 65% lower for 10 MV photon beams than for their corresponding Co-60 photon beams.
CONCLUSION: The genetically significant dose from Hodgkin's treatment (less than 0.01 mSv) adds about 4% to the genetically significant dose contribution to medical procedures and adds less than 1% to the genetically significant dose from all sources. Therefore, the consequence to society is considered to be very small. The consequences for the individual patient are, likewise, small.

Entities:  

Mesh:

Substances:

Year:  1993        PMID: 8454491     DOI: 10.1016/0360-3016(93)90023-o

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  1 in total

1.  Adaptive planning using megavoltage fan-beam CT for radiation therapy with testicular shielding.

Authors:  Poonam Yadav; Kevin Kozak; Ranjini Tolakanahalli; V Ramasubramanian; Bhudatt R Paliwal; James S Welsh; Yi Rong
Journal:  Med Dosim       Date:  2011-09-16       Impact factor: 1.482

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.