Literature DB >> 8454294

D21S210: a highly polymorphic (GT)n marker closely linked to the beta-amyloid protein precursor (APP) gene.

A C Warren1, M G McInnis, M Kalaitsidaki, T K Cox, J Blaschak, A Chakravarti, S E Antonarakis.   

Abstract

We describe a highly polymorphic (GT)n repeat with 14 alleles that is closely linked to the amyloid precursor protein (APP) gene on human chromosome 21. This marker, D21S210, will be useful for studies of linkage of disorders such as Alzheimer disease to the APP gene.

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Year:  1993        PMID： 8454294     DOI： 10.1007/bf00230232

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  1 in total

1.  An efficient method for selecting unique-sequence clones from DNA libraries and its application to fluorescent staining of human chromosome 21 using in situ hybridization.

Authors:  J C Fuscoe; C C Collins; D Pinkel; J W Gray
Journal:  Genomics       Date:  1989-07       Impact factor: 5.736
  1 in total
  5 in total

1.  Molecular mapping of 21 features associated with partial monosomy 21: involvement of the APP-SOD1 region.

Authors:  Z Chettouh; M F Croquette; B Delobel; S Gilgenkrants; C Leonard; C Maunoury; M Prieur; M O Rethoré; P M Sinet; M Chery
Journal:  Am J Hum Genet       Date:  1995-07       Impact factor: 11.025

2.  Genetic and physical mapping of the GLUR5 glutamate receptor gene on human chromosome 21.

Authors:  P Gregor; S M Gaston; X Yang; J P O'Regan; D R Rosen; R E Tanzi; D Patterson; J L Haines; H R Horvitz; G R Uhl
Journal:  Hum Genet       Date:  1994-11       Impact factor: 4.132

3.  No founder effect in three novel Alzheimer's disease families with APP 717 Val-->Ile mutation. Clerget-darpoux. French Alzheimer's Disease Study Group.

Authors:  D Campion; A Brice; D Hannequin; F Charbonnier; B Dubois; C Martin; A Michon; C Penet; M Bellis; A Calenda; M Martinez; Y Agid; F Clerget-Darpoux; T Frebourg
Journal:  J Med Genet       Date:  1996-08       Impact factor: 6.318

4.  A large, dominant pedigree of atrioventricular septal defect (AVSD): exclusion from the Down syndrome critical region on chromosome 21.

Authors:  L Wilson; A Curtis; J R Korenberg; R D Schipper; L Allan; G Chenevix-Trench; A Stephenson; J Goodship; J Burn
Journal:  Am J Hum Genet       Date:  1993-12       Impact factor: 11.025

5.  A population-based study of familial Alzheimer disease: linkage to chromosomes 14, 19, and 21.

Authors:  C M van Duijn; L Hendriks; L A Farrer; H Backhovens; M Cruts; A Wehnert; A Hofman; C Van Broeckhoven
Journal:  Am J Hum Genet       Date:  1994-10       Impact factor: 11.025
  5 in total

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