Literature DB >> 8453274

Cyclin D and oncogenesis.

T Motokura1, A Arnold.   

Abstract

The D-type cyclins are among the candidate 'G1 cyclins' in higher eukaryotes that may regulate G1-S-phase progression. The human cyclin D1 gene, also known as PRAD1 (and previously as D11S287), is a putative proto-oncogene strongly implicated in several types of human tumors, including parathyroid adenomas, B-cell neoplasms (as the 'BCL-1 oncogene'), and breast and squamous cell cancers. The mechanism by which deregulated production of cyclin D1/PRAD1, and perhaps other D-type cyclins, contributes to tumor development is only beginning to be deciphered.

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Year:  1993        PMID： 8453274     DOI： 10.1016/s0959-437x(05)80334-x

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN： 0959-437X            Impact factor:   5.578


  60 in total

1.  Hormone autotrophic growth and differentiation identifies mutant lines of Arabidopsis with altered cytokinin and auxin content or signaling.

Authors:  M Frank; H M Rupp; E Prinsen; V Motyka; H Van Onckelen; T Schmülling
Journal:  Plant Physiol       Date:  2000-03       Impact factor: 8.340

2.  Chromosomal and extrachromosomal instability of the cyclin D2 gene is induced by Myc overexpression.

Authors:  S Mai; J Hanley-Hyde; G J Rainey; T I Kuschak; J T Paul; T D Littlewood; H Mischak; L M Stevens; D W Henderson; J F Mushinski
Journal:  Neoplasia       Date:  1999-08       Impact factor: 5.715

Review 3.  Clinico-prognostic value of D-type cyclins and p27 in laryngeal cancer patients: a review.

Authors:  L Pignataro; G Sambataro; D Pagani; G Pruneri
Journal:  Acta Otorhinolaryngol Ital       Date:  2005-04       Impact factor: 2.124

4.  Role of cyclins in neuronal differentiation of immortalized hippocampal cells.

Authors:  W Xiong; R Pestell; M R Rosner
Journal:  Mol Cell Biol       Date:  1997-11       Impact factor: 4.272

Review 5.  Molecular predictors of clinical outcome in patients with head and neck squamous cell carcinoma.

Authors:  Giovana R Thomas; Hari Nadiminti; Jacinto Regalado
Journal:  Int J Exp Pathol       Date:  2005-12       Impact factor: 1.925

6.  Amplification and overexpression of the cyclin D1 gene in head and neck squamous cell carcinoma.

Authors:  X Wang; Z P Pavelic; Y Q Li; L Wang; L Gleich; K Radack; J L Gluckman; P J Stambrook
Journal:  Clin Mol Pathol       Date:  1995-10

7.  Increased expression of cyclin D2 during multiple states of growth arrest in primary and established cells.

Authors:  M Meyyappan; H Wong; C Hull; K T Riabowol
Journal:  Mol Cell Biol       Date:  1998-06       Impact factor: 4.272

Review 8.  Progress against cancer.

Authors:  S Broder; J E Karp
Journal:  J Cancer Res Clin Oncol       Date:  1995       Impact factor: 4.553

9.  Gastrokine-2 is downregulated in gastric cancer and its restoration suppresses gastric tumorigenesis and cancer metastasis.

Authors:  Jin Dai; Ning Zhang; Jinhui Wang; Minhu Chen; Jie Chen
Journal:  Tumour Biol       Date:  2014-01-10

10.  Developmental regulation of CYCA2s contributes to tissue-specific proliferation in Arabidopsis.

Authors:  Steffen Vanneste; Frederik Coppens; Eunkyoung Lee; Tyler J Donner; Zidian Xie; Gert Van Isterdael; Stijn Dhondt; Freya De Winter; Bert De Rybel; Marnik Vuylsteke; Lieven De Veylder; Jiří Friml; Dirk Inzé; Erich Grotewold; Enrico Scarpella; Fred Sack; Gerrit T S Beemster; Tom Beeckman
Journal:  EMBO J       Date:  2011-07-19       Impact factor: 11.598
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