Literature DB >> 8452668

Nuclear signaling by interleukin-6.

S Chen-Kiang1, W Hsu, Y Natkunam, X Zhang.   

Abstract

The molecular analysis of the regulation of nuclear proteins induced by interleukin-6 has provided new insights into this largely unknown signal transduction pathway. Transcription factors of the CCAAT/enhancer-binding protein and AP-1 families, as well as the octamer-binding proteins and the tumor suppressor gene product pRB, are regulated by interleukin-6 in a cell type specific manner, suggesting that they may play a role in the nuclear signaling by interleukin-6.

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Year:  1993        PMID: 8452668     DOI: 10.1016/0952-7915(93)90091-6

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN: 0952-7915            Impact factor:   7.486


  10 in total

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Review 2.  Multiple myeloma: increasing evidence for a multistep transformation process.

Authors:  M Hallek; P L Bergsagel; K C Anderson
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Review 3.  IL-6-like cytokines and cancer cachexia: consequences of chronic inflammation.

Authors:  B E Barton
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4.  Toll-Like Receptor-3 Mediates HIV-1-Induced Interleukin-6 Expression in the Human Brain Endothelium via TAK1 and JNK Pathways: Implications for Viral Neuropathogenesis.

Authors:  Biju Bhargavan; Georgette D Kanmogne
Journal:  Mol Neurobiol       Date:  2017-11-11       Impact factor: 5.590

5.  The human topoisomerase I gene promoter is regulated by NF-IL6.

Authors:  S Heiland; R Knippers
Journal:  Mol Cell Biol       Date:  1995-12       Impact factor: 4.272

6.  NF-IL6 and AP-1 cooperatively modulate the activation of the TSG-6 gene by tumor necrosis factor alpha and interleukin-1.

Authors:  L Klampfer; T H Lee; W Hsu; J Vilcek; S Chen-Kiang
Journal:  Mol Cell Biol       Date:  1994-10       Impact factor: 4.272

7.  Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region.

Authors:  W Hsu; T K Kerppola; P L Chen; T Curran; S Chen-Kiang
Journal:  Mol Cell Biol       Date:  1994-01       Impact factor: 4.272

8.  Multiple regions within the cytoplasmic domains of the leukemia inhibitory factor receptor and gp130 cooperate in signal transduction in hepatic and neuronal cells.

Authors:  H Baumann; A J Symes; M R Comeau; K K Morella; Y Wang; D Friend; S F Ziegler; J S Fink; D P Gearing
Journal:  Mol Cell Biol       Date:  1994-01       Impact factor: 4.272

9.  Induction of the mouse serum amyloid A3 gene by cytokines requires both C/EBP family proteins and a novel constitutive nuclear factor.

Authors:  J H Huang; W S Liao
Journal:  Mol Cell Biol       Date:  1994-07       Impact factor: 4.272

10.  Non-Canonical Role of IKKα in the Regulation of STAT1 Phosphorylation in Antiviral Signaling.

Authors:  Fei Xing; Tomoh Matsumiya; Yuko Shiba; Ryo Hayakari; Hidemi Yoshida; Tadaatsu Imaizumi
Journal:  PLoS One       Date:  2016-12-19       Impact factor: 3.240

  10 in total

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