Literature DB >> 8452667

Glucocorticoids, lipocortins and the immune response.

N J Goulding1, P M Guyre.   

Abstract

Glucocorticoids are immunosuppressive and antiinflammatory agents that act through multiple mechanisms. This review highlights recent evidence that lipocortin-1, a member of the annexin family of calcium-binding proteins, can be induced by glucocorticoids, and may mediate some of the effects of glucocorticoids through putative lipocortin-1 receptors, which have been found on the surface of phagocytic cells. Recent advances in annexin biology have been drawn together to formulate a novel hypothesis for the regulation of inflammation.

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Year:  1993        PMID: 8452667     DOI: 10.1016/0952-7915(93)90089-b

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN: 0952-7915            Impact factor:   7.486


  28 in total

1.  Purification and inhibitory profile of phospholipase A2 inhibitors from Australian elapid sera.

Authors:  P G Hains; K W Broady
Journal:  Biochem J       Date:  2000-02-15       Impact factor: 3.857

2.  The inhibitory effect of dexamethasone on lymphocyte adhesion molecule expression and intercellular aggregation is not mediated by lipocortin 1.

Authors:  N J Goulding; S Ogbourn; N Pipitone; P Biagini; R Gerli; C Pitzalis
Journal:  Clin Exp Immunol       Date:  1999-12       Impact factor: 4.330

3.  Glucocorticoids enhance concanavalin A-induced mitogenic response through the inhibition of nitric oxide production.

Authors:  F Ramírez; A Silva
Journal:  Immunology       Date:  1997-01       Impact factor: 7.397

Review 4.  An association between corticosteroid use and melanoma recurrence: a case report and review of the literature.

Authors:  Mark Lazarus; Howard Kaufman
Journal:  Med Oncol       Date:  2011-09-16       Impact factor: 3.064

5.  Annexins I and II bind to lipid A: a possible role in the inhibition of endotoxins.

Authors:  D A Eberhard; S R Vandenberg
Journal:  Biochem J       Date:  1998-02-15       Impact factor: 3.857

6.  Characterization of a novel anti-inflammatory factor produced by RM3/1 macrophages derived from glucocorticoid treated human monocytes.

Authors:  W Hamann; A Flöter; W Schmutzler; G Zwadlo-Klarwasser
Journal:  Inflamm Res       Date:  1995-12       Impact factor: 4.575

7.  The influence of IL-7 V(D)J recombination.

Authors:  U Döbbeling
Journal:  Immunology       Date:  1996-12       Impact factor: 7.397

8.  Decrease of 12-hydroxyeicosatetraenoic acid production in mouse lungs following dietary oleic anilide consumption: implications for the toxic oil syndrome.

Authors:  S H Yoshida; B A Bruenner; J B German; M E Gershwin
Journal:  Arch Environ Contam Toxicol       Date:  1995-05       Impact factor: 2.804

9.  Glucocorticoid deficiency increases phospholipase A2 activity in rats.

Authors:  B S Vishwanath; F J Frey; M J Bradbury; M F Dallman; B M Frey
Journal:  J Clin Invest       Date:  1993-10       Impact factor: 14.808

10.  Dexamethasone enhances interaction of endogenous annexin 1 with L-selectin and triggers shedding of L-selectin in the monocytic cell line U-937.

Authors:  Catherine de Coupade; Egle Solito; Jon D Levine
Journal:  Br J Pharmacol       Date:  2003-08-11       Impact factor: 8.739

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