Literature DB >> 8451033

Antitumor-promoting activity of scopadulcic acid B, isolated from the medicinal plant Scoparia dulcis L.

H Nishino1, T Hayashi, M Arisawa, Y Satomi, A Iwashima.   

Abstract

Scopadulcic acid B (SDB), a tetracyclic diterpenoid isolated from a medicinal plant, Scoparia dulcis L., inhibited the effects of tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) in vitro and in vivo; SDB inhibited TPA-enhanced phospholipid synthesis in cultured cells, and also suppressed the promoting effect of TPA on skin tumor formation in mice initiated with 7,12-dimethylbenz[a]anthracene. The potency of SDB proved to be stronger than that of other natural antitumor-promoting terpenoids, such as glycyrrhetinic acid.

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Year:  1993        PMID： 8451033     DOI： 10.1159/000227156

Source DB:  PubMed          Journal:  Oncology        ISSN： 0030-2414            Impact factor:   2.935


  7 in total

1.  Endophytic Penicillium citrinum Thom. from Scoparia dulcis Linn.

Authors:  Annie J Mathew; K Jayachandran; Jyothis Mathew
Journal:  Indian J Microbiol       Date:  2010-11-25       Impact factor: 2.461

2.  Biolistic transformation of Scoparia dulcis L.

Authors:  Kota Srinivas; Narra Muralikrishna; Kalva Bharath Kumar; Ellendula Raghu; Aileni Mahender; Kasula Kiranmayee; Velivela Yashodahara; Abbagani Sadanandam
Journal:  Physiol Mol Biol Plants       Date:  2016-01-20

3.  Cytokinin induced shoot regeneration and flowering of Scoparia dulcis L. (Scrophulariaceae)-an ethnomedicinal herb.

Authors:  G Premkumar; R Sankaranarayanan; S Jeeva; K Rajarathinam
Journal:  Asian Pac J Trop Biomed       Date:  2011-06

4.  Ethnopharmacological survey among migrants living in the Southeast Atlantic Forest of Diadema, São Paulo, Brazil.

Authors:  Daniel Garcia; Marcus Vinicius Domingues; Eliana Rodrigues
Journal:  J Ethnobiol Ethnomed       Date:  2010-10-29       Impact factor: 2.733

5.  Ethnopharmacology of medicinal plants of the pantanal region (mato grosso, Brazil).

Authors:  Isanete Geraldini Costa Bieski; Fabrício Rios Santos; Rafael Melo de Oliveira; Mariano Martinez Espinosa; Miramy Macedo; Ulysses Paulino Albuquerque; Domingos Tabajara de Oliveira Martins
Journal:  Evid Based Complement Alternat Med       Date:  2012-02-26       Impact factor: 2.629

6.  Evaluation of anticancer potential of Thai medicinal herb extracts against cholangiocarcinoma cell lines.

Authors:  Bundit Promraksa; Jutarop Phetcharaburanin; Nisana Namwat; Anchalee Techasen; Patcharee Boonsiri; Watcharin Loilome
Journal:  PLoS One       Date:  2019-05-23       Impact factor: 3.240

7.  Antisickling and toxicological evaluation of the leaves of Scoparia dulcis Linn (Scrophulariaceae).

Authors:  Tavs A Abere; Chiagozie J Okoye; Freddy O Agoreyo; Gerald I Eze; Rose I Jesuorobo; Clement O Egharevba; Pauline O Aimator
Journal:  BMC Complement Altern Med       Date:  2015-11-23       Impact factor: 3.659
  7 in total

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