| Literature DB >> 8450325 |
M Chbani1, M Païs, J M Delauneux, C Debitus.
Abstract
Chemical investigation of the cytotoxic CH2Cl2-soluble extract of the marine tunicate Pseudodistoma arborescens led to the isolation of four brominated indole alkaloids, arborescidines A [1], B [2], C [3], and D [4], which were characterized by their spectral data, especially 2D nmr. Only arborescidine D [4] showed moderate activity (IC50 3 micrograms/ml) in vitro against the growth of KB human buccal carbinoma cells.Entities:
Mesh：
Substances：
Year: 1993 PMID： 8450325 DOI： 10.1021/np50091a014
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050