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Literature DB >> 844895

Endothelial adenine uptake as an assay for cell- or complement-mediated cytotoxicity.

D P DeBono, D E Macintyre, D J White, J L Gordon.

Abstract

[3H] Adenine uptake by monolayers of cultured pig aortic endothelium was characterized and used as the basis for a terminal adenine uptake cytotoxicity assay. This assay was used to demonstrate specific cytotoxicity against donor-type endothelium by serum and by peripheral blood lymphocytes from skin-graft allergized pigs, and to compare the time course of these two types of effector mechanism.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1977 PMID： 844895 PMCID： PMC1445219

Source DB: PubMed Journal: Immunology ISSN： 0019-2805 Impact factor: 7.397

6 in total

1. Stimulation of human lymphocytes by cultured allogeneic skin and endothelial cells in vitro.

Authors: H Hirschberg; S A Evensen; T Henriksen; E Thorsby
Journal: Transplantation Date: 1975-02 Impact factor: 4.939

2. Preservation of tissue culture cells with liquid nitrogen.

Authors: J NAGINGTON; R I GREAVES
Journal: Nature Date: 1962-06-09 Impact factor: 49.962

3. Histocompatibility phenotyping by the mixed lymphocyte reaction.

Authors: B A Bradley; J M Edwards; D Franks
Journal: Tissue Antigens Date: 1973

4. Endothelial cell stimulation of allogeneic lymphocytes.

Authors: R M Vetto; D R Burger
Journal: Transplantation Date: 1972-11 Impact factor: 4.939

5. The relationship of the histocompatibility locus in the pig to allograft survival.

Authors: D J White; B Bradley; R Y Calne; R M Binns
Journal: Transplant Proc Date: 1973-03 Impact factor: 1.066

6. Interaction of pig lymphocytes with allogenic kidney cells in vitro.

Authors: M R Daniel; M J Edwards
Journal: Br J Exp Pathol Date: 1975-08

6 in total

5 in total

1. Modification of lymphocyte responsiveness in vitro by lambda carrageenan compared with colloidal silica and depletion of surface adherent cells.

Authors: G Pawelec; G Brons
Journal: Clin Exp Immunol Date: 1978-03 Impact factor: 4.330

Endothelial adenine uptake as an assay for cell- or complement-mediated cytotoxicity.

1. Stimulation of human lymphocytes by cultured allogeneic skin and endothelial cells in vitro.

2. Preservation of tissue culture cells with liquid nitrogen.

3. Histocompatibility phenotyping by the mixed lymphocyte reaction.

4. Endothelial cell stimulation of allogeneic lymphocytes.

5. The relationship of the histocompatibility locus in the pig to allograft survival.

6. Interaction of pig lymphocytes with allogenic kidney cells in vitro.

1. Modification of lymphocyte responsiveness in vitro by lambda carrageenan compared with colloidal silica and depletion of surface adherent cells.

2. Endothelium-derived relaxing factor reduces platelet adhesion to bovine endothelial cells.

3. Plasma or serum from patients with systemic sclerosis alters behaviour of normal erythrocytes.

4. Effects of hyperoxia on biochemical indexes of pig aortic endothelial function.

5. The induction of suppressor cells in mixed leucocyte cultures and in mixed leucocyte-non-lymphoid cell cultures.