| Literature DB >> 8448567 |
Abstract
A method is described for 67Ga-labeling liposomes containing a polyethylene glycol coating which exhibit prolonged blood circulation, reduced liver and spleen uptake and accumulation in tumors. Applications as agents for diagnostic imaging and delivery of therapeutic agents are considered. Previous methods were adapted to compensate for the presence of low temperature phase transition phospholipids resulting in consistent loading with low levels of residual unentrapped label.Entities:
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Year: 1993 PMID: 8448567 DOI: 10.1016/0969-8051(93)90107-6
Source DB: PubMed Journal: Nucl Med Biol ISSN: 0969-8051 Impact factor: 2.408