| Literature DB >> 844561 |
K Blum, J E Wallace, E Meyer, H A Schwertner.
Abstract
Methysergide, a serotonergic receptor blocker, was studied to determine its effects against d-amphetamine-induced excitation as measured by convulsions elicited by handling in mice. Significant intensification (p less than 0.01) of the action of d-amphetamine was observed in mice. These results indicate that reduction in serotonergic activity in the central nervous system enhances excitation induced by d-amphetamine.Entities:
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Year: 1977 PMID： 844561 DOI： 10.1007/BF02124073
Source DB: PubMed Journal: Experientia ISSN： 0014-4754