Literature DB >> 8444087

Colonic mucosal pH in humans.

C J McDougall1, R Wong, P Scudera, M Lesser, J J DeCosse.   

Abstract

Mucosal pH was measured at specific anatomic segments within the colon using a flexible pH probe in patients prepared for colonoscopy. The data revealed similar pH measurements along the length of the colon, irrespective of the presence or absence of colorectal neoplasia. Patients exhibited a relatively acidic right colon; a more alkaline transverse, left, and sigmoid colon; and a relatively acidic rectum. There were no apparent gender- or age-related effects on colonic mucosal pH.

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Year:  1993        PMID： 8444087     DOI： 10.1007/bf01316512

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN： 0163-2116            Impact factor:   3.199


  24 in total

1.  ABSORPTION OF SHORT CHAIN FATTY ACIDS IN MAN.

Authors:  A M DAWSON; C D HOLDSWORTH; J WEBB
Journal:  Proc Soc Exp Biol Med       Date:  1964-10

2.  Ion transport by rabbit colon. I. Active and passive components.

Authors:  R A Frizzell; M J Koch; S G Schultz
Journal:  J Membr Biol       Date:  1976       Impact factor: 1.843

3.  Faecal pH value and its modification by dietary means in South African black and white schoolchildren.

Authors:  A R Walker; B F Walker; I Segal
Journal:  S Afr Med J       Date:  1979-03-24

4.  Measurement of gastrointestinal pH profiles in normal ambulant human subjects.

Authors:  D F Evans; G Pye; R Bramley; A G Clark; T J Dyson; J D Hardcastle
Journal:  Gut       Date:  1988-08       Impact factor: 23.059

5.  Electrophysiology of the human colon: evidence of segmental heterogeneity.

Authors:  G I Sandle; N K Wills; W Alles; H J Binder
Journal:  Gut       Date:  1986-09       Impact factor: 23.059

6.  Large-bowel cancer in Hawaiian Japanese.

Authors:  W Haenszel; J W Berg; M Segi; M Kurihara; F B Locke
Journal:  J Natl Cancer Inst       Date:  1973-12       Impact factor: 13.506

Review 7.  The etiology of gastric cancer. Intragastric nitrosamide formation and other theories.

Authors:  S S Mirvish
Journal:  J Natl Cancer Inst       Date:  1983-09       Impact factor: 13.506

8.  Rabbit proximal colon: a distinct transport epithelium.

Authors:  J H Sellin; R DeSoignie
Journal:  Am J Physiol       Date:  1984-05

9.  Mucosal surface pH of the large intestine of the rat and of normal and inflamed large intestine in man.

Authors:  N I McNeil; K L Ling; J Wager
Journal:  Gut       Date:  1987-06       Impact factor: 23.059

10.  Effects of lactulose and other laxatives on ileal and colonic pH as measured by a radiotelemetry device.

Authors:  R L Bown; J A Gibson; G E Sladen; B Hicks; A M Dawson
Journal:  Gut       Date:  1974-12       Impact factor: 23.059
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  11 in total

1.  Differential effects of mucosal pH on human (Caco-2) intestinal epithelial cell motility, proliferation, and differentiation.

Authors:  D A Perdikis; R Davies; A Zhuravkov; B Brenner; L Etter; M D Basson
Journal:  Dig Dis Sci       Date:  1998-07       Impact factor: 3.199

2.  Extracellular pH regulates zinc signaling via an Asp residue of the zinc-sensing receptor (ZnR/GPR39).

Authors:  Limor Cohen; Hila Asraf; Israel Sekler; Michal Hershfinkel
Journal:  J Biol Chem       Date:  2012-08-09       Impact factor: 5.157

Review 3.  Intestinal luminal pH in inflammatory bowel disease: possible determinants and implications for therapy with aminosalicylates and other drugs.

Authors:  S G Nugent; D Kumar; D S Rampton; D F Evans
Journal:  Gut       Date:  2001-04       Impact factor: 23.059

Review 4.  Pectin matrix as oral drug delivery vehicle for colon cancer treatment.

Authors:  Tin Wui Wong; Gaia Colombo; Fabio Sonvico
Journal:  AAPS PharmSciTech       Date:  2010-12-31       Impact factor: 3.246

Review 5.  The intestinal absorption of folates.

Authors:  Michele Visentin; Ndeye Diop-Bove; Rongbao Zhao; I David Goldman
Journal:  Annu Rev Physiol       Date:  2014       Impact factor: 19.318

6.  A single-component multidrug transporter of the major facilitator superfamily is part of a network that protects Escherichia coli from bile salt stress.

Authors:  Stephanie Paul; Kamela O Alegre; Scarlett R Holdsworth; Matthew Rice; James A Brown; Paul McVeigh; Sharon M Kelly; Christopher J Law
Journal:  Mol Microbiol       Date:  2014-04-13       Impact factor: 3.501

7.  Microbial Metabolic Capacity for Intestinal Folate Production and Modulation of Host Folate Receptors.

Authors:  Melinda A Engevik; Christina N Morra; Daniel Röth; Kristen Engevik; Jennifer K Spinler; Sridevi Devaraj; Sue E Crawford; Mary K Estes; Markus Kalkum; James Versalovic
Journal:  Front Microbiol       Date:  2019-10-09       Impact factor: 5.640

8.  Lactic Acidosis Interferes With Toxicity of Perifosine to Colorectal Cancer Spheroids: Multimodal Imaging Analysis.

Authors:  Barbora Pavlatovská; Markéta Machálková; Petra Brisudová; Adam Pruška; Karel Štěpka; Jan Michálek; Tereza Nečasová; Petr Beneš; Jan Šmarda; Jan Preisler; Michal Kozubek; Jarmila Navrátilová
Journal:  Front Oncol       Date:  2020-12-04       Impact factor: 6.244

Review 9.  Akkermansia muciniphila in the Human Gastrointestinal Tract: When, Where, and How?

Authors:  Sharon Y Geerlings; Ioannis Kostopoulos; Willem M de Vos; Clara Belzer
Journal:  Microorganisms       Date:  2018-07-23

10.  Magnesium Sensing Regulates Intestinal Colonization of Enterohemorrhagic Escherichia coli O157:H7.

Authors:  Yutao Liu; Runhua Han; Junyue Wang; Pan Yang; Fang Wang; Bin Yang
Journal:  mBio       Date:  2020-11-10       Impact factor: 7.867
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