Literature DB >> 8443055

Constitutive heterochromatin polymorphisms in children with acute lymphoblastic leukemia.

A Tsezou1, S Kitsiou-Tzeli, H Kosmidis, K Paidousi, K Katsouyanni, C Sinaniotis.   

Abstract

The C-band heterochromatin polymorphisms of chromosomes 1, 9, and 16 were studied on peripheral lymphocytes of 67 children with acute lymphoblastic leukemia (ALL) and 50 control individuals. A statistically significant difference between patients and controls was found for large heterochromatin regions (level 3) of chromosomes 1 and 9 (P < 0.001) and for small heterochromatin regions (level 1) of chromosome 16 (P < 0.001). The patients also showed a significant increase in chromosomes 1 and 9 heteromorphism with respect to controls (P < 0.001).

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Year:  1993        PMID: 8443055     DOI: 10.3109/08880019309016522

Source DB:  PubMed          Journal:  Pediatr Hematol Oncol        ISSN: 0888-0018            Impact factor:   1.969


  2 in total

1.  Acquired pericentric inversion of chromosome 9 in essential thrombocythemia.

Authors:  T S Wan; S K Ma; L C Chan
Journal:  Hum Genet       Date:  2000-06       Impact factor: 4.132

2.  Utility of chromosomal position of heterochromatin as a biomarker of radiation-induced genetic damage: a study of Chornobyl voles (Microtus sp.).

Authors:  Lara E Wiggins; Ronald A Van Den Bussche; Meredith J Hamilton; Ronald K Chesser; Robert J Baker
Journal:  Ecotoxicology       Date:  2002-06       Impact factor: 2.823

  2 in total

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