Literature DB >> 844298

Mechanism of cinnamaldehyde sensitization.

V A Majeti, R R Suskind.   

Abstract

The skin sensitization of cinnamaldehyde is probably initiated by the reaction of cinnamaldehyde with epsilon-amino groups on protein side chains. Alpha-Substituted cinnamaldehydes, which are known not to be skin sensitizers, react very slowly or not at all with amines in comparison with cinnamaldehyde.

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Year:  1977        PMID: 844298     DOI: 10.1111/j.1600-0536.1977.tb03581.x

Source DB:  PubMed          Journal:  Contact Dermatitis        ISSN: 0105-1873            Impact factor:   6.600


  3 in total

1.  Effect of food flavor cinnamaldehyde on liver microsomal cytochrome P-450 in rats.

Authors:  H Devaraj; S Niranjali; M Raveendran
Journal:  Bull Environ Contam Toxicol       Date:  1992-08       Impact factor: 2.151

2.  Isolation and identification of mercapturic acids of cinnamic aldehyde and cinnamyl alcohol from urine of female rats.

Authors:  L P Delbressine; P J Klippert; J T Reuvers; F Seuttler-Berlage
Journal:  Arch Toxicol       Date:  1981-11       Impact factor: 5.153

3.  Determination of Protein Haptenation by Chemical Sensitizers Within the Complexity of the Human Skin Proteome.

Authors:  Erika Parkinson; Maja Aleksic; Richard Cubberley; Gushinder Kaur-Atwal; Johannes P C Vissers; Paul Skipp
Journal:  Toxicol Sci       Date:  2018-04-01       Impact factor: 4.849

  3 in total

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