Literature DB >> 8442893

Prenatal alcohol exposure attenuates pentylenetetrazol-induced convulsions in rats.

E L Abel1, R F Berman, M W Church.   

Abstract

Female rats prenatally exposed to alcohol were tested at 35 days of age for susceptibility to pentylenetetrazol (PTZ)-induced convulsions. There was a significant dose-response effect of PTZ. Contrary to expectations, alcohol-exposed females were slightly but still significantly less convulsion-prone than pair-fed controls. These results suggest prenatal alcohol exposure reduces the susceptibility to convulsions in rats.

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Year:  1993        PMID: 8442893     DOI: 10.1016/0741-8329(93)90096-7

Source DB:  PubMed          Journal:  Alcohol        ISSN: 0741-8329            Impact factor:   2.405


  2 in total

1.  Prenatal alcohol exposure enhances the susceptibility to NMDA-induced generalized tonic-clonic seizures in developing rats.

Authors:  Sue J Cho; David M Lovinger; Prosper N'Gouemo
Journal:  CNS Neurosci Ther       Date:  2017-10       Impact factor: 5.243

2.  Embryonic exposure to ethanol increases the susceptibility of larval zebrafish to chemically induced seizures.

Authors:  Keling Wang; Xiaopan Chen; Jie Liu; Li-Ping Zou; Wenke Feng; Lu Cai; Xiaoyang Wu; Shao-Yu Chen
Journal:  Sci Rep       Date:  2018-01-30       Impact factor: 4.379

  2 in total

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