Literature DB >> 844192

The clearance of lipoprotein X in vitro, and effect of phospholipase A on serum lipoprotein X.

J Rubies-Prat, M R Ras, J C Frison, S Masdeu, R Bacardi.   

Abstract

The in vitro effect of post-heparin and post-heparin plus post-protamine normal serum on serum lipoprotein X (LP-X) is described. Serum LP-X is cleared after incubation with post-heparin normal serum, and serum LP-X remain unmodified when it is incubated with post-heparin plus post-protamine normal serum. The action of phospholipase A from snake venom on serum LP-X is also studied. A very small quantity of phospholipase is necessary to degrade LP-X and to transform lecithin into lysolecithin. It is concluded that phospholipase seems to be the enzyme that most likely induces the LP-X changes after heparin administration.

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Year:  1977        PMID: 844192     DOI: 10.1016/0009-8981(77)90506-x

Source DB:  PubMed          Journal:  Clin Chim Acta        ISSN: 0009-8981            Impact factor:   3.786


  2 in total

1.  A role for POR1, a Rac1-interacting protein, in ARF6-mediated cytoskeletal rearrangements.

Authors:  C D'Souza-Schorey; R L Boshans; M McDonough; P D Stahl; L Van Aelst
Journal:  EMBO J       Date:  1997-09-01       Impact factor: 11.598

2.  Lipoprotein X Causes Renal Disease in LCAT Deficiency.

Authors:  Alice Ossoli; Edward B Neufeld; Seth G Thacker; Boris Vaisman; Milton Pryor; Lita A Freeman; Christine A Brantner; Irina Baranova; Nicolás O Francone; Stephen J Demosky; Cecilia Vitali; Monica Locatelli; Mauro Abbate; Carlamaria Zoja; Guido Franceschini; Laura Calabresi; Alan T Remaley
Journal:  PLoS One       Date:  2016-02-26       Impact factor: 3.240

  2 in total

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