Literature DB >> 84415

The expression of histocompatibility-2 antigens on hemopoietic stem cells.

J L Russell, G van den Engh.   

Abstract

Antisera directed against histocompatibility-2 antigens of the mouse suppress the formation of spleen colonies by pluripotent hemopoietic stem cells. Of antisera which are specific for subregions of the H-2 complex, only those which contain anti-H-2K or anti-H-2D activity are effective. Specific anti-Ia sera do not react with the stem cell. If the titer of the CFU-s suppressive effect of the antisera is compared to their toxicity to spleen lymphocytes, it can be concluded that CFU-s express antigens in the same density as spleen lymphocytes. The amount of H-2 antigens expressed on the surface of CFU-s is independent of its rate of proliferation.

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Year:  1979        PMID： 84415     DOI： 10.1111/j.1399-0039.1979.tb01135.x

Source DB:  PubMed          Journal:  Tissue Antigens        ISSN： 0001-2815


  5 in total

1.  Antigen presentation safeguards the integrity of the hematopoietic stem cell pool.

Authors:  Pablo Hernández-Malmierca; Dominik Vonficht; Alexandra Schnell; Hannah J Uckelmann; Alina Bollhagen; Mohamed A A Mahmoud; Sophie-Luise Landua; Elise van der Salm; Christine L Trautmann; Simon Raffel; Florian Grünschläger; Raphael Lutz; Michael Ghosh; Simon Renders; Nádia Correia; Elisa Donato; Karin O Dixon; Christoph Hirche; Carolin Andresen; Claudia Robens; Paula S Werner; Tobias Boch; David Eisel; Wolfram Osen; Franziska Pilz; Adriana Przybylla; Corinna Klein; Frank Buchholz; Michael D Milsom; Marieke A G Essers; Stefan B Eichmüller; Wolf-Karsten Hofmann; Daniel Nowak; Daniel Hübschmann; Michael Hundemer; Christian Thiede; Lars Bullinger; Carsten Müller-Tidow; Scott A Armstrong; Andreas Trumpp; Vijay K Kuchroo; Simon Haas
Journal:  Cell Stem Cell       Date:  2022-05-05       Impact factor: 25.269

2.  Isolation of a candidate human hematopoietic stem-cell population.

Authors:  C M Baum; I L Weissman; A S Tsukamoto; A M Buckle; B Peault
Journal:  Proc Natl Acad Sci U S A       Date:  1992-04-01       Impact factor: 11.205

3.  T-cell depletion of bone marrow does not inhibit in vitro hematopoiesis.

Authors:  J Kirshner; H Ozer; M O'Leary; D Higby; M Marinello; H Preisler
Journal:  Blut       Date:  1985-04

4.  A new class of cell surface antigens. Quantitative absorption studies defining cell-lineage-specific antigens on hemopoietic cells.

Authors:  M V Berridge
Journal:  J Exp Med       Date:  1979-10-01       Impact factor: 14.307

5.  Immune regulation of in vitro murine megakaryocyte development. Role of T lymphocytes and Ia antigen expression.

Authors:  M W Long; D N Shapiro
Journal:  J Exp Med       Date:  1985-12-01       Impact factor: 14.307
  5 in total

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