Literature DB >> 8441337

Reduction of fatty acid hydroperoxides by human parotid saliva.

J Terao1, A Nagao, H Yuki, Y Itoh.   

Abstract

Arachidonic acid hydroperoxide (15-hydroperoxyeicosatetraenoic acid; 15-HPETE) was introduced into human parotid saliva and incubated at 37 degrees C. Straight phase high-performance liquid chromatography analysis of the reaction mixture showed that 15-HPETE was detoxified to its reduced form, 15-hydroxyeicosatetraenoic acid, in the presence of glutathione. Therefore, it is concluded that human parotid saliva possesses fatty acid hydroperoxide-reducing ability. However, its effectiveness was found to be lower than that of blood plasma.

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Year:  1993        PMID: 8441337     DOI: 10.1007/bf02535775

Source DB:  PubMed          Journal:  Lipids        ISSN: 0024-4201            Impact factor:   1.880


  20 in total

1.  The effect of dietary lipid hydroperoxide on lymphoid tissues in mice.

Authors:  M Oarada; E Ito; K Terao; T Miyazawa; K Fujimoto; T Kaneda
Journal:  Biochim Biophys Acta       Date:  1988-05-22

2.  Antioxidant enzymes in rat gastrointestinal tract.

Authors:  M Manohar; K A Balasubramanian
Journal:  Indian J Biochem Biophys       Date:  1986-10       Impact factor: 1.918

3.  Sensitivity of feeding tests in detecting carcinogenic properties in chemicals: examination of 7,12-dimethylbenz(a)anthracene and oxidized linoleate.

Authors:  M G Cutler; R Schneider
Journal:  Food Cosmet Toxicol       Date:  1973-06

4.  Absorption and metabolism of 1-14C-methyl linoleate hydroperoxide.

Authors:  J G Bergan; H H Draper
Journal:  Lipids       Date:  1970-12       Impact factor: 1.880

5.  Intracellular mechanisms for the decomposition of a lipid peroxide. I. Decomposition of a lipid peroxide by metal ions, heme compounds, and nucleophiles.

Authors:  P J O'Brien
Journal:  Can J Biochem       Date:  1969-05

6.  Use of exogenous glutathione for metabolism of peroxidized methyl linoleate in rat small intestine.

Authors:  D P Kowalski; R M Feeley; D P Jones
Journal:  J Nutr       Date:  1990-09       Impact factor: 4.798

7.  Preparation and purification of lipid hydroperoxides from arachidonic and gamma-linolenic acids.

Authors:  M O Funk; R Isacc; N A Porter
Journal:  Lipids       Date:  1976-02       Impact factor: 1.880

8.  Protective action of phospholipid hydroperoxide glutathione peroxidase against membrane-damaging lipid peroxidation. In situ reduction of phospholipid and cholesterol hydroperoxides.

Authors:  J P Thomas; M Maiorino; F Ursini; A W Girotti
Journal:  J Biol Chem       Date:  1990-01-05       Impact factor: 5.157

9.  The influence of phospholipase A2 and glutathione peroxidase on the elimination of membrane lipid peroxides.

Authors:  A Sevanian; S F Muakkassah-Kelly; S Montestruque
Journal:  Arch Biochem Biophys       Date:  1983-06       Impact factor: 4.013

10.  Uptake of secondary autoxidation products of linoleic acid by the rat.

Authors:  K Kanazawa; E Kanazawa; M Natake
Journal:  Lipids       Date:  1985-07       Impact factor: 1.880

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  3 in total

1.  Phospholipid hydroperoxides are detoxified by phospholipase A2 and GSH peroxidase in rat gastric mucosa.

Authors:  Sayuri Miyamoto; Coralie Dupas; Kaeko Murota; Junji Terao
Journal:  Lipids       Date:  2003-06       Impact factor: 1.880

Review 2.  The Relationship Between Salivary Redox, Diet, and Food Flavor Perception.

Authors:  Mathieu Schwartz; Fabrice Neiers; Gilles Feron; Francis Canon
Journal:  Front Nutr       Date:  2021-01-28

3.  Plasma HDL reduces nonesterified fatty acid hydroperoxides originating from oxidized LDL: a mechanism for its antioxidant ability.

Authors:  Mari Kotosai; Sachiko Shimada; Mai Kanda; Namiko Matsuda; Keiko Sekido; Yoshibumi Shimizu; Akira Tokumura; Toshiyuki Nakamura; Kaeko Murota; Yoshichika Kawai; Junji Terao
Journal:  Lipids       Date:  2013-03-14       Impact factor: 1.880

  3 in total

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