Literature DB >> 8441106

Elevated 1,25-dihydroxyvitamin D serum concentrations in infants with subcutaneous fat necrosis.

K Kruse1, U Irle, R Uhlig.   

Abstract

Two infants with subcutaneous fat necrosis had hypercalcemia that normalized during glucocorticoid treatment. The combination of hypercalcemia, normal concentration of 25-hydroxyvitamin D, an elevated concentration of 1,25-dihydroxyvitamin D, a suppressed parathyroid hormone level, and low-normal bone turnover indicated abnormal 1,25-dihydroxyvitamin D production with increased intestinal absorption of calcium. Unregulated production of 1,25-dihydroxyvitamin D by the granulomatous cells of fat necrosis may cause hypercalcemia.

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Year:  1993        PMID： 8441106     DOI： 10.1016/s0022-3476(05)83441-9

Source DB:  PubMed          Journal:  J Pediatr        ISSN： 0022-3476            Impact factor:   4.406


  6 in total

1.  Symptomatic hypercalcemia in the first months of life: calcium-regulating hormones and treatment.

Authors:  P Ghirri; U Bottone; L Coccoli; M Bernardini; M Vuerich; A Cuttano; C Riparbelli; G Pellegrinetti; A Boldrini
Journal:  J Endocrinol Invest       Date:  1999-05       Impact factor: 4.256

2.  Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in subcutaneous fat necrosis.

Authors:  A Farooque; C Moss; D Zehnder; M Hewison; N J Shaw
Journal:  Br J Dermatol       Date:  2008-09-20       Impact factor: 9.302

3.  Severe neonatal hypercalcemia caused by subcutaneous fat necrosis without any apparent cutaneous lesion.

Authors:  Laurent Bonnemains; Stephanie Rouleau; Gaelle Sing; Claude Bouderlique; Regis Coutant
Journal:  Eur J Pediatr       Date:  2008-03-26       Impact factor: 3.183

4.  Subcutaneous fat necrosis of the newborn associated with hypercalcaemia.

Authors:  H M Lewis; S Ferryman; A R Gatrad; C Moss
Journal:  J R Soc Med       Date:  1994-08       Impact factor: 18.000

5.  Subcutaneous Fat Necrosis of the Newborn: A Case Report of a Term Infant Presenting with Malaise and Fever at Age of 9 Weeks.

Authors:  Ayuk Adaeze Chikaodinaka; Anikene Chukwuemeka Jude
Journal:  Case Rep Pediatr       Date:  2015-10-08

6.  Severe Thrombocytosis in a Newborn with Subcutaneous Fat Necrosis and Maternal Chorioamnionitis.

Authors:  Mitali Sahni; Pooja Patel; Akila Muthukumar
Journal:  Case Rep Hematol       Date:  2020-02-21
  6 in total

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