| Literature DB >> 8440142 |
A A Bergen1, M C Wapenaar, E J Schuurman, P J Diergaarde, H Lerach, A P Monaco, E Bakker, E M Bleeker-Wagemakers, G J van Ommen.
Abstract
Differential Alu PCR fingerprint cloning was used to isolate a DNA probe from the Xp11.4-->p11.21 region of the human X chromosome. This novel sequence, cpXr318 (DXS742), detects a new submicroscopic deletion interval at the Norrie disease locus (NDP). Combining our data with the consensus genetic map of the proximal short arm of the X chromosome, we propose the physical order Xcen-DXS14-DXS255-(DXS426, TIMP)-(DXS742-([MAOB-MAOA-DXS7], NDP)-DXS77-DXS228)-DXS209-DXS148-DXS196-++ +Xpter. The cpXr318 probe and a subclone from a cosmid corresponding to the DXS7 locus were converted into sequence-tagged sites. Finally, DXS742, DSX7, DXS77, and MAOA were integrated into a physical map spanning the Norrie disease locus.Entities:
Mesh：
Substances：
Year: 1993 PMID： 8440142 DOI： 10.1159/000133484
Source DB: PubMed Journal: Cytogenet Cell Genet ISSN： 0301-0171