Literature DB >> 843989

Fate of orally dosed linamarin in the rat.

M D Barrett, D C Hill, J C Alexander, A Zitnak.   

Abstract

Wistar rats, about 100 g in weight, were dosed by stomach tube with 30 mg of pure linamarin. No intact linamarin was identified in the feces or blood but 5.65 mg was excreted in the urine along with 0.823 mg of thiocyanate ion. A 50-mg dose of linamarin was lethal to 7 of 10 rats receiving this dose.

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Year:  1977        PMID： 843989     DOI： 10.1139/y77-021

Source DB:  PubMed          Journal:  Can J Physiol Pharmacol        ISSN： 0008-4212            Impact factor:   2.273


  3 in total

1.  Amygdalin toxicity studies in rats predict chronic cyanide poisoning in humans.

Authors:  G W Newton; E S Schmidt; J P Lewis; E Conn; R Lawrence
Journal:  West J Med       Date:  1981-02

2.  Effect of Dose and Administration Period of Seed Cake of Genetically Modified and Non-Modified Flax on Selected Antioxidative Activities in Rats.

Authors:  Magdalena Matusiewicz; Iwona Kosieradzka; Magdalena Zuk; Jan Szopa
Journal:  Int J Mol Sci       Date:  2015-06-23       Impact factor: 5.923

3.  Bioavailability of cyanide after consumption of a single meal of foods containing high levels of cyanogenic glycosides: a crossover study in humans.

Authors:  Klaus Abraham; Thorsten Buhrke; Alfonso Lampen
Journal:  Arch Toxicol       Date:  2015-02-24       Impact factor: 5.153
  3 in total

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