OBJECTIVE: To assess the height outcome of newborns born small for gestational age. DESIGN: A historical prospective study. SETTING: A cohort of 1758 newborns born at a single university hospital maternity ward and subsequently examined at the military draft medical board at age 17 years. PARTICIPANTS: Newborns whose weight at birth was below the third percentile were defined as small for gestational age. Their body measurements at age 17 years were compared with those of their peers who were appropriate for gestational age. MEASUREMENTS/MAIN RESULTS: The adjusted mean +/- SEM height for boys born small for gestational age vs peers born appropriate for gestational age was 169.9 +/- 1.5 vs 175.4 +/- 0.8 cm (P < .0001); and for girls, 159.4 +/- 1.3 vs 163.1 +/- 0.8 cm (P < .0005). In addition, the risk for height attainment below the 10th percentile was significantly increased for newborns born small for gestational age. The adjusted odds ratio was 4.13 for boys (95% confidence interval, 1.66 to 10.25; P < .0006) and 3.32 for girls (95% confidence interval, 1.38 to 8.05; P < .0005). CONCLUSION: Infants born small for gestational age may be at increased risk for short stature in late adolescence.
OBJECTIVE: To assess the height outcome of newborns born small for gestational age. DESIGN: A historical prospective study. SETTING: A cohort of 1758 newborns born at a single university hospital maternity ward and subsequently examined at the military draft medical board at age 17 years. PARTICIPANTS: Newborns whose weight at birth was below the third percentile were defined as small for gestational age. Their body measurements at age 17 years were compared with those of their peers who were appropriate for gestational age. MEASUREMENTS/MAIN RESULTS: The adjusted mean +/- SEM height for boys born small for gestational age vs peers born appropriate for gestational age was 169.9 +/- 1.5 vs 175.4 +/- 0.8 cm (P < .0001); and for girls, 159.4 +/- 1.3 vs 163.1 +/- 0.8 cm (P < .0005). In addition, the risk for height attainment below the 10th percentile was significantly increased for newborns born small for gestational age. The adjusted odds ratio was 4.13 for boys (95% confidence interval, 1.66 to 10.25; P < .0006) and 3.32 for girls (95% confidence interval, 1.38 to 8.05; P < .0005). CONCLUSION:Infants born small for gestational age may be at increased risk for short stature in late adolescence.
Authors: J N Hirschhorn; C M Lindgren; M J Daly; A Kirby; S F Schaffner; N P Burtt; D Altshuler; A Parker; J D Rioux; J Platko; D Gaudet; T J Hudson; L C Groop; E S Lander Journal: Am J Hum Genet Date: 2001-06-15 Impact factor: 11.025
Authors: Susan Harlap; A Michael Davies; Lisa Deutsch; Ronit Calderon-Margalit; Orly Manor; Ora Paltiel; Efrat Tiram; Rivka Yanetz; Mary C Perrin; Mary B Terry; Dolores Malaspina; Yechiel Friedlander Journal: Paediatr Perinat Epidemiol Date: 2007-05 Impact factor: 3.980
Authors: Sandra G Wai; Paul J Rozance; Stephanie R Wesolowski; William W Hay; Laura D Brown Journal: Am J Physiol Endocrinol Metab Date: 2018-09-11 Impact factor: 4.310
Authors: Nir Melamed; Ahmet Baschat; Yoav Yinon; Apostolos Athanasiadis; Federico Mecacci; Francesc Figueras; Vincenzo Berghella; Amala Nazareth; Muna Tahlak; H David McIntyre; Fabrício Da Silva Costa; Anne B Kihara; Eran Hadar; Fionnuala McAuliffe; Mark Hanson; Ronald C Ma; Rachel Gooden; Eyal Sheiner; Anil Kapur; Hema Divakar; Diogo Ayres-de-Campos; Liran Hiersch; Liona C Poon; John Kingdom; Roberto Romero; Moshe Hod Journal: Int J Gynaecol Obstet Date: 2021-03 Impact factor: 3.561
Authors: Griffith A Bell; Rajeshwari Sundaram; Sunni L Mumford; Hyojun Park; Miranda Broadney; James L Mills; Erin M Bell; Edwina H Yeung Journal: J Epidemiol Community Health Date: 2018-05-22 Impact factor: 3.710