OBJECTIVE: To evaluate the association between fetal loss in the second trimester and subsequent adverse birth outcomes. METHODS: We identified 95 women in our system who had a pregnancy loss at 13-24 weeks in the years 1985-1990 and tabulated the rates of preterm delivery, stillbirth, and neonatal death in the next pregnancy. We compared these outcomes to two groups: women who delivered at 25-36 weeks in their index pregnancy and those who delivered at term in their index pregnancy. RESULTS: Thirty-nine percent of women who had a pregnancy loss at 13-24 weeks in the index pregnancy had a preterm delivery in their next pregnancy, 5% had a stillbirth, and 6% had a neonatal death, with all outcomes worse than those found in the two control populations. Delivery at 19-22 weeks in the index pregnancy was associated with a 62% preterm delivery rate in the subsequent pregnancy. CONCLUSION: A second-trimester loss, especially one occurring at 19-22 weeks, is associated with a poor prognosis in the subsequent pregnancy.
OBJECTIVE: To evaluate the association between fetal loss in the second trimester and subsequent adverse birth outcomes. METHODS: We identified 95 women in our system who had a pregnancy loss at 13-24 weeks in the years 1985-1990 and tabulated the rates of preterm delivery, stillbirth, and neonatal death in the next pregnancy. We compared these outcomes to two groups: women who delivered at 25-36 weeks in their index pregnancy and those who delivered at term in their index pregnancy. RESULTS: Thirty-nine percent of women who had a pregnancy loss at 13-24 weeks in the index pregnancy had a preterm delivery in their next pregnancy, 5% had a stillbirth, and 6% had a neonatal death, with all outcomes worse than those found in the two control populations. Delivery at 19-22 weeks in the index pregnancy was associated with a 62% preterm delivery rate in the subsequent pregnancy. CONCLUSION: A second-trimester loss, especially one occurring at 19-22 weeks, is associated with a poor prognosis in the subsequent pregnancy.
Authors: Heleen J Schuster; Myrthe J C S Peelen; Petra J Hajenius; Monique D M van Beukering; Rik van Eekelen; Marit Schonewille; Henna Playfair; Joris A M van der Post; Marjolein Kok; Rebecca C Painter Journal: Health Sci Rep Date: 2022-05-24
Authors: Michel A Makhlouf; Rebecca G Clifton; James M Roberts; Leslie Myatt; John C Hauth; Kenneth J Leveno; Michael W Varner; John M Thorp; Brian M Mercer; Alan M Peaceman; Susan M Ramin; Jay D Iams; Anthony Sciscione; Jorge E Tolosa; Yoram Sorokin Journal: Am J Perinatol Date: 2013-12-17 Impact factor: 1.862
Authors: K B Smith-Dupont; C E Wagner; J Witten; K Conroy; H Rudoltz; K Pagidas; V Snegovskikh; M House; K Ribbeck Journal: Sci Rep Date: 2017-09-04 Impact factor: 4.379