Literature DB >> 8437613

Cell wall fractions from Paracoccidioides brasiliensis induce hypergammaglobulinemia.

S L de Oliveira1, M F da Silva, A M Soares, C L Silva.   

Abstract

The antibody response against the antigen sheep red blood cells (SRBC) was investigated in mice pre-treated with formalin-killed Paracoccidioides brasiliensis or with cell wall fractions of the fungus. Pre-treatment with P. brasiliensis, as well as with the Fl fraction and beta-glucan significantly increased the anti-SRBC antibody response in the experimental groups as compared to the control group that received only SRBC. This immunomodulatory effect varied with the different doses employed and with pre-treatment time. We conclude that the cell wall fractions of P. brasiliensis might play an important role in the hypergammaglobulinemia associated with Paracoccidioidomycosis.

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Year:  1993        PMID: 8437613     DOI: 10.1007/bf01103346

Source DB:  PubMed          Journal:  Mycopathologia        ISSN: 0301-486X            Impact factor:   2.574


  14 in total

1.  Serial enzymatic hydrolysis of cell walls of two serotypes of yeast-form Histoplasma capsulatum with alpha(1 leads to 3)-glucanase, beta(1 leads to 3)-glucanase, pronase, and chitinase.

Authors:  E Reiss
Journal:  Infect Immun       Date:  1977-04       Impact factor: 3.441

2.  Two types of mouse helper T-cell clone Implications for immune regulation.

Authors:  T R Mosmann; R L Coffman
Journal:  Immunol Today       Date:  1987

3.  Induction of antigen-specific T suppressor cells by soluble Paracoccidioides brasiliensis antigen.

Authors:  B E Jimenez-Finkel; J W Murphy
Journal:  Infect Immun       Date:  1988-04       Impact factor: 3.441

4.  Modulatory effect of glucans on the functional and biochemical activities of guinea-pig macrophages.

Authors:  M Ferencík; D Kotulová; L Masler; L Bergendi; J Sandula; J Stefanovic
Journal:  Methods Find Exp Clin Pharmacol       Date:  1986-03

5.  Host defense against experimental paracoccidioidomycosis.

Authors:  M A Robledo; J R Graybill; J Ahrens; A Restrepo; D J Drutz; M Robledo
Journal:  Am Rev Respir Dis       Date:  1982-05

6.  Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

Authors:  T R Mosmann; H Cherwinski; M W Bond; M A Giedlin; R L Coffman
Journal:  J Immunol       Date:  1986-04-01       Impact factor: 5.422

7.  The role of fractions from Paracoccidioides brasiliensis in the genesis of inflammatory response.

Authors:  L M Alves; F Figueiredo; S L Brandão Filho; I Tincani; C L Silva
Journal:  Mycopathologia       Date:  1987-01       Impact factor: 2.574

8.  Biochemical studies on the thermal dimorphism of Paracoccidioides brasiliensis.

Authors:  F Kanetsuna; L M Carbonell; I Azuma; Y Yamamura
Journal:  J Bacteriol       Date:  1972-04       Impact factor: 3.490

Review 9.  Current status and perspectives of immunomodulators of microbial origin.

Authors:  G Chihara; Y Y Maeda; J Hamuro
Journal:  Int J Tissue React       Date:  1982

10.  Role of the thymus in directing the development of a subset of B lymphocytes.

Authors:  J J Mond; I Scher; J Cossman; S Kessler; P K Mongini; C Hansen; F D Finkelman; W E Paul
Journal:  J Exp Med       Date:  1982-03-01       Impact factor: 14.307

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  3 in total

1.  Differential correlation between interleukin patterns in disseminated and chronic human paracoccidioidomycosis.

Authors:  C L Silva; M F Silva; L H Faccioli; R C Pietro; S A Cortez; N T Foss
Journal:  Clin Exp Immunol       Date:  1995-08       Impact factor: 4.330

2.  TGF-beta and CD23 are involved in nitric oxide production by pulmonary macrophages activated by beta-glucan from Paracoccidioides brasiliensis.

Authors:  Luiz de Pádua Queiroz; Marden Estevão Mattos; Marcelo Fernandes da Silva; Célio Lopes Silva
Journal:  Med Microbiol Immunol       Date:  2009-12-01       Impact factor: 3.402

3.  The paracoccidioides cell wall: past and present layers toward understanding interaction with the host.

Authors:  Rosana Puccia; Milene Carmes Vallejo; Alisson Leonardo Matsuo; Larissa Valle Guilhen Longo
Journal:  Front Microbiol       Date:  2011-12-20       Impact factor: 5.640

  3 in total

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