Literature DB >> 8437498

[Technique and results of hyperthermic perfusion of the extremity in melanoma patients].

G Omlor1, F Bahmer, S Meessen, D Zang, G Feifel, H Zaun.   

Abstract

The results of hyperthermic isolated limb perfusion therapy in 36 patients with stage II-IV malignant melanoma of the extremities are presented. With the technique employed, neither severe complications nor functional deficiencies attributable to the perfusion therapy were observed. The findings on follow-up for up to 36 months are comparable to those reported in the literature, with survival rates of about 90% for stage II and III patients and nearly 50% for stage IV patients. Thus, our technique appears to be beneficial, especially in respect of the very low rate of side effects.

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Year:  1993        PMID: 8437498

Source DB:  PubMed          Journal:  Langenbecks Arch Chir        ISSN: 0023-8236


  16 in total

1.  Extraperitoneal approach to the abdominal aorta.

Authors:  C ROB
Journal:  Surgery       Date:  1963-01       Impact factor: 3.982

2.  Hyperthermic perfusion with chemotherapy for melanoma of the extremities.

Authors:  F Ghussen; I Krüger; R V Smalley; W Groth
Journal:  World J Surg       Date:  1989 Sep-Oct       Impact factor: 3.352

3.  Isolated limb perfusion for localized melanoma of the extremity. A matched comparison of wide local excision with isolated limb perfusion and wide local excision alone.

Authors:  M J Edwards; S J Soong; A W Boddie; C M Balch; C M McBride
Journal:  Arch Surg       Date:  1990-03

4.  Regional isolation perfusion in melanoma of the limbs; accomplishments, unsolved problems, future.

Authors:  B B Kroon
Journal:  Eur J Surg Oncol       Date:  1988-04       Impact factor: 4.424

5.  Functional morbidity after regional isolated perfusion of the limb for melanoma.

Authors:  A N van Geel; J van Wijk; J Wieberdink
Journal:  Cancer       Date:  1989-03-15       Impact factor: 6.860

6.  Hyperthermic isolated regional perfusion in the treatment of extremity melanoma in children and adolescents.

Authors:  P C Baas; H J Hoekstra; H Schraffordt Koops; W J Oosterhuis; L T van der Weele
Journal:  Cancer       Date:  1989-01-01       Impact factor: 6.860

7.  Impact of regional chemotherapy for melanoma metastases.

Authors:  H Voigt
Journal:  Anticancer Res       Date:  1988 May-Jun       Impact factor: 2.480

8.  Hyperthermic perfusion with chemotherapy for cancers of the extremities.

Authors:  J S Stehlin
Journal:  Surg Gynecol Obstet       Date:  1969-08

Review 9.  Isolated limb perfusion for melanoma: effectiveness and toxicity of cisplatin compared with that of melphalan and other drugs.

Authors:  J F Thompson; M P Gianoutsos
Journal:  World J Surg       Date:  1992 Mar-Apr       Impact factor: 3.352

10.  A simple and accurate new method for cytostatics dosimetry in isolation perfusion of the limbs based on exchangeable blood volume determination.

Authors:  F J Lejeune; G E Ghanem
Journal:  Cancer Res       Date:  1987-01-15       Impact factor: 12.701

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