BACKGROUND: Crystalglobulinemia syndrome (CS) is a rare vasculopathy that may arise as a complication of multiple myeloma (MM). METHODS AND RESULTS: A patient with multiple myeloma in whom crystalglobulinemia syndrome was the initial manifestation with polyarthralgias, cutaneous ulceration, and lower limb ischemia requiring bilateral amputations is reported. CONCLUSION: The rare syndrome of crystalglobulinemia may be associated with multiple myeloma, so it is important that clinicians be aware of this syndrome and its clinical and morphologic features.
BACKGROUND:Crystalglobulinemia syndrome (CS) is a rare vasculopathy that may arise as a complication of multiple myeloma (MM). METHODS AND RESULTS: A patient with multiple myeloma in whom crystalglobulinemia syndrome was the initial manifestation with polyarthralgias, cutaneous ulceration, and lower limb ischemia requiring bilateral amputations is reported. CONCLUSION: The rare syndrome of crystalglobulinemia may be associated with multiple myeloma, so it is important that clinicians be aware of this syndrome and its clinical and morphologic features.
Authors: Bolesław Papla; Paweł Spólnik; Ewa Rzenno; Andrzej Zduńczyk; Zbigniew Rudzki; Krzysztof Okoń; Wojciech Szczepański; Wojciech Dabroś; Jerzy Stachura Journal: Virchows Arch Date: 2004-05-12 Impact factor: 4.064
Authors: Matthew R D'Costa; Lauren A Dalvin; Sandhya Manohar; Leo J Maguire; Joseph P Grande; Wilson I Gonsalves; Samih H Nasr; Marie C Hogan Journal: Kidney Med Date: 2019-02-25