OBJECTIVE: To assess long term survival (> 5 years) and quality of life in severely ill patients referred for urgent cardiac transplantation. SETTING: Tertiary referral centres: before transplantation at the National Heart Hospital (late 1984 to end 1986); after transplantation at Harefield Hospital. SUBJECTS: Eighteen patients (15 men; three women) who had required intensive support in hospital before cardiac transplantation and were alive at short term follow up. INTERVENTIONS: Intravenous infusions of cardiac drugs (mean 2.2 infusions), intravenous diuretics (17 patients), and many other drugs before transplantation. Intra-aortic balloon counterpulsation (four patients), temporary pacing (two), and resuscitation from cardiac arrest (three). Patients had specialised nursing care on a medical intensive care unit in almost every case. MAIN OUTCOME MEASURES: Long term survival in patients after urgent cardiac transplantation and perceived quality of life. RESULTS: Of 18 patients who were alive at short term follow up (mean (range) 19.4 (10-33) months), 14 were still alive in 1992 (69 (61-83) months). Ten still worked full time, and 11 reported no restrictions in their daily activities. Three of four patients who died in the intervening period survived > 5 years after transplantation. Overall, 17 of 18 patients survived at least 5 years. CONCLUSIONS: In severely ill patients who undergo urgent cardiac transplantation and survive in the short term, long term (5-7 year) survival and quality of life seem good.
OBJECTIVE: To assess long term survival (> 5 years) and quality of life in severely ill patients referred for urgent cardiac transplantation. SETTING: Tertiary referral centres: before transplantation at the National Heart Hospital (late 1984 to end 1986); after transplantation at Harefield Hospital. SUBJECTS: Eighteen patients (15 men; three women) who had required intensive support in hospital before cardiac transplantation and were alive at short term follow up. INTERVENTIONS: Intravenous infusions of cardiac drugs (mean 2.2 infusions), intravenous diuretics (17 patients), and many other drugs before transplantation. Intra-aortic balloon counterpulsation (four patients), temporary pacing (two), and resuscitation from cardiac arrest (three). Patients had specialised nursing care on a medical intensive care unit in almost every case. MAIN OUTCOME MEASURES: Long term survival in patients after urgent cardiac transplantation and perceived quality of life. RESULTS: Of 18 patients who were alive at short term follow up (mean (range) 19.4 (10-33) months), 14 were still alive in 1992 (69 (61-83) months). Ten still worked full time, and 11 reported no restrictions in their daily activities. Three of four patients who died in the intervening period survived > 5 years after transplantation. Overall, 17 of 18 patients survived at least 5 years. CONCLUSIONS: In severely ill patients who undergo urgent cardiac transplantation and survive in the short term, long term (5-7 year) survival and quality of life seem good.
Authors: R M Lewis; C T Van Buren; B Radovancevic; O H Frazier; R P Janney; P L Powers; D L Golden; J G Giannakis; M P Macris; R H Kerman Journal: J Heart Lung Transplant Date: 1991 Jan-Feb Impact factor: 10.247
Authors: A H Menkis; R J Novick; W J Kostuk; P W Pflugfelder; A M Powell; D Thomson; F N McKenzie Journal: J Heart Lung Transplant Date: 1991 Jan-Feb Impact factor: 10.247
Authors: J E Reedy; D G Pennington; L W Miller; L R McBride; D P Lohmann; N R Noedel; M T Swartz Journal: J Heart Lung Transplant Date: 1992 Mar-Apr Impact factor: 10.247
Authors: S Birovljev; B Radovancevic; C M Burnett; J D Vega; G Bennink; J L Lonquist; J M Duncan; O H Frazier Journal: J Heart Lung Transplant Date: 1992 Mar-Apr Impact factor: 10.247
Authors: P W Pflugfelder; N R Singh; F N McKenzie; A H Menkis; R J Novick; W J Kostuk Journal: J Heart Lung Transplant Date: 1991 May-Jun Impact factor: 10.247
Authors: Kathleen L Grady; David C Naftel; James B Young; Dave Pelegrin; Jennifer Czerr; Robert Higgins; Alain Heroux; Bruce Rybarczyk; Mary McLeod; Jon Kobashigawa; Julie Chait; Connie White-Williams; Susan Myers; James K Kirklin Journal: J Heart Lung Transplant Date: 2007-09-27 Impact factor: 10.247