Literature DB >> 8435438

Relationships between age-dependent changes in the effect of almitrine on H(+)-ATPase/ATPsynthase and the pattern of membrane fatty acid composition.

M Jumelle-Laclau1, M Rigoulet, N Averet, X Leverve, L Dubourg, A Carbonneau, M Clerc, B Guerin.   

Abstract

The effects of almitrine on ATPase/ATPsynthase previously described in beef heart mitochondria (Rigoulet et al. (1990) Biochim. Biophys. Acta 1018, 91-97) are also observed in liver mitochondria isolated from rats older than 7 weeks. In contrast, in rats younger than 5 weeks, almitrine at the same concentration has no effect on the ATPase/ATPsynthase complex. This age-dependent action of almitrine is well correlated with age-dependent modifications of two fatty acids: linoleic and docosahexaenoic acids. The possibility of a change in H+/ATP stoichiometry of the ATPase/ATPsynthase induced by almitrine seems related to more general modifications of membrane properties during growth of the rat.

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Year:  1993        PMID： 8435438     DOI： 10.1016/0005-2728(93)90193-j

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  6 in total

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2.  Cold acclimation or grapeseed oil feeding affects phospholipid composition and mitochondrial function in duckling skeletal muscle.

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Authors:  B Aguilaniu; P Flore; H Perrault; J E Page; E Payan; J R Lacour
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4.  Localization of PTP-1B, SHP-2, and Src exclusively in rat brain mitochondria and functional consequences.

Authors:  Amal Arachiche; Olivier Augereau; Marion Decossas; Claire Pertuiset; Etienne Gontier; Thierry Letellier; Jeanne Dachary-Prigent
Journal:  J Biol Chem       Date:  2008-06-26       Impact factor: 5.157

5.  Oxidative phosphorylation in intact hepatocytes: quantitative characterization of the mechanisms of change in efficiency and cellular consequences.

Authors:  X Leverve; B Sibille; A Devin; M A Piquet; P Espié; M Rigoulet
Journal:  Mol Cell Biochem       Date:  1998-07       Impact factor: 3.396

6.  70-kDa heat shock protein expression in cultured rat astrocytes after hypoxia: regulatory effect of almitrine.

Authors:  J C Copin; E Pinteaux; M Ledig; G Tholey
Journal:  Neurochem Res       Date:  1995-01       Impact factor: 3.996
  6 in total

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