Literature DB >> 8435395

Visual loss in an onchocerciasis endemic community in Sierra Leone.

J A Whitworth1, C E Gilbert, D M Mabey, D Morgan, A Foster.   

Abstract

The visual acuities of 1625 individuals recruited to a community-based clinical trial of ivermectin in southern Sierra Leone were measured, and the prevalence of visual loss in this rural population where onchocerciasis is hyperendemic was determined. Ocular examination was performed before treatment to establish the cause of visual loss. Using WHO definitions, 1.3% were blind (less than 3/60 in both eyes), 4.3% were visually impaired (between 6/24 and 3/60 in the better eye), and a further 3.4% were uniocularly blind (less than 3/60 in one eye and better than 6/24 in the other). Cataract and onchocerciasis were the major causes of visual loss in this population. More than half of the ocular morbidity was preventable or treatable by public health measures or basic curative medicine. These findings are discussed in the light of the available health and eye care services.

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Year:  1993        PMID: 8435395      PMCID: PMC504418          DOI: 10.1136/bjo.77.1.30

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  13 in total

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Journal:  Acta Leiden       Date:  1990

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Journal:  Br J Ophthalmol       Date:  1989-02       Impact factor: 4.638

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Journal:  Bull World Health Organ       Date:  1979       Impact factor: 9.408

5.  Effects of repeated doses of ivermectin on ocular onchocerciasis: community-based trial in Sierra Leone.

Authors:  J A Whitworth; C E Gilbert; D M Mabey; G H Maude; D Morgan; D W Taylor
Journal:  Lancet       Date:  1991-11-02       Impact factor: 79.321

6.  The evolution of ocular onchocerciasis in the Volta River Basin Area over a period of five years of vector control.

Authors:  K Y Dadzie; A Rolland; B Thylefors
Journal:  Tropenmed Parasitol       Date:  1984-03

7.  Causes and prevalence of blindness in the Northern Province of Sierra Leone.

Authors:  J S Stilma; S Bridger
Journal:  Doc Ophthalmol       Date:  1983-12-15       Impact factor: 2.379

8.  The distribution of the Simulium damnosum complex in Sierra Leone and its relation to onchocerciasis.

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Journal:  Ann Trop Med Parasitol       Date:  1985-04

9.  Blindness and visual impairment in southern Malawi.

Authors:  M C Chirambo; J M Tielsch; K P West; J Katz; T Tizazu; L Schwab; G Johnson; J Swartwood; H R Taylor; A Sommer
Journal:  Bull World Health Organ       Date:  1986       Impact factor: 9.408

10.  Blindness in the Midwestern State of Nigeria.

Authors:  J O Ayanru
Journal:  Trop Geogr Med       Date:  1974-09
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  10 in total

Review 1.  Doxycycline plus ivermectin versus ivermectin alone for treatment of patients with onchocerciasis.

Authors:  Ayokunle T Abegunde; Richard M Ahuja; Nkem J Okafor
Journal:  Cochrane Database Syst Rev       Date:  2016-01-15

Review 2.  The possible impact of uveitis in blindness: a literature survey.

Authors:  M S Suttorp-Schulten; A Rothova
Journal:  Br J Ophthalmol       Date:  1996-09       Impact factor: 4.638

3.  Prevalence of blindness in people over 40 years in the volta region of ghana.

Authors:  J P Guzek; F K Anyomi; S Fiadoyor; F Nyonator
Journal:  Ghana Med J       Date:  2005-06

4.  Blindness and visual impairment in an urban West African population: the Tema Eye Survey.

Authors:  Donald L Budenz; Jagadeesh R Bandi; Keith Barton; Winifred Nolan; Leon Herndon; Julia Whiteside-de Vos; Graham Hay-Smith; Hanna Kim; James Tielsch
Journal:  Ophthalmology       Date:  2012-06-05       Impact factor: 12.079

5.  Blindness from uveitis in a hospital population in Sierra Leone.

Authors:  M J Ronday; J S Stilma; R F Barbe; A Kijlstra; A Rothova
Journal:  Br J Ophthalmol       Date:  1994-09       Impact factor: 4.638

6.  Incidence of visual loss in rural southwest Uganda.

Authors:  S M Mbulaiteye; B C Reeves; F Mulwanyi; J A G Whitworth; G Johnson
Journal:  Br J Ophthalmol       Date:  2003-07       Impact factor: 4.638

7.  Study of onchocerciasis-related visual impairment in North Kivu province of the Democratic Republic of Congo in Africa.

Authors:  Vinod K Baranwal; Kripanidhi Shyamsundar; Vamble Kabuyaya; Jyotirmay Biswas; Harikrishnan Vannadil
Journal:  Indian J Ophthalmol       Date:  2020-05       Impact factor: 1.848

8.  Economic evaluations of onchocerciasis interventions: a systematic review and research needs.

Authors:  Hugo C Turner; Martin Walker; Sébastien D S Pion; Deborah A McFarland; Donald A P Bundy; María-Gloria Basáñez
Journal:  Trop Med Int Health       Date:  2019-05-09       Impact factor: 2.622

9.  How does onchocerciasis-related skin and eye disease in Africa depend on cumulative exposure to infection and mass treatment?

Authors:  Natalie V S Vinkeles Melchers; Wilma A Stolk; Michele E Murdoch; Belén Pedrique; Marielle Kloek; Roel Bakker; Sake J de Vlas; Luc E Coffeng
Journal:  PLoS Negl Trop Dis       Date:  2021-06-11

10.  Impact of three rounds of mass drug administration on lymphatic filariasis in areas previously treated for onchocerciasis in Sierra Leone.

Authors:  Joseph B Koroma; Santigie Sesay; Mustapha Sonnie; Mary H Hodges; Foday Sahr; Yaobi Zhang; Moses J Bockarie
Journal:  PLoS Negl Trop Dis       Date:  2013-06-13
  10 in total

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