Literature DB >> 8435383

A negative association of schizophrenia with an allele of the HLA DQB1 gene among African-Americans.

V L Nimgaonkar1, R Ganguli, W A Rudert, C Vavassori, B S Rabin, M Trucco.   

Abstract

Using polymorphisms of the human leukocyte antigen (HLA) DQB1 gene, a case-control study was conducted in a group of patients with schizophrenia (DSM-III, n = 58) and psychiatrically normal controls matched for ethnicity (n = 72), living in the same geographical area. A significant negative association of allele HLA DQB1*0602 with schizophrenia was present among African-Americans (odds ratio 0.19), but could not be detected in Caucasians.

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Year:  1993        PMID: 8435383     DOI: 10.1016/0920-9964(93)90018-e

Source DB:  PubMed          Journal:  Schizophr Res        ISSN: 0920-9964            Impact factor:   4.939


  8 in total

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Review 2.  Molecular genetics of schizophrenia: past, present and future.

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Journal:  Schizophr Bull       Date:  2012-09-10       Impact factor: 9.306

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7.  HLA-A*11:01 is associated with levetiracetam-induced psychiatric adverse events.

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Journal:  PLoS One       Date:  2018-07-18       Impact factor: 3.240

8.  Immunity and mental illness: findings from a Danish population-based immunogenetic study of seven psychiatric and neurodevelopmental disorders.

Authors:  Ron Nudel; Michael E Benros; Morten Dybdahl Krebs; Rosa Lundbye Allesøe; Camilla Koldbæk Lemvigh; Jonas Bybjerg-Grauholm; Anders D Børglum; Mark J Daly; Merete Nordentoft; Ole Mors; David M Hougaard; Preben Bo Mortensen; Alfonso Buil; Thomas Werge; Simon Rasmussen; Wesley K Thompson
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  8 in total

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