Literature DB >> 8432529

The human interleukin-1 receptor antagonist (IL1RN) gene is located in the chromosome 2q14 region.

D Patterson1, C Jones, I Hart, J Bleskan, R Berger, D Geyer, S P Eisenberg, M F Smith, W P Arend.   

Abstract

The gene for human interleukin-1 receptor antagonist (IL1RN) has been assigned to chromosome 2 on the basis of Southern blot analysis of a series of human-Chinese hamster cell hybrids. Using a yeast artificial chromosome containing the IL1RN gene as a probe, the human IL1RN gene was localized to the long arm of chromosome 2 at band 2q14.2 by fluorescence in situ hybridization. This site is near the positions of genes for human IL-1 alpha, IL-1 beta, and types I and II IL-1 receptors, as reported by other laboratories.

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Year:  1993        PMID: 8432529     DOI: 10.1006/geno.1993.1025

Source DB:  PubMed          Journal:  Genomics        ISSN: 0888-7543            Impact factor:   5.736


  12 in total

1.  Gestational drive and the green-bearded placenta.

Authors:  D Haig
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-25       Impact factor: 11.205

Review 2.  Biological role of interleukin 1 receptor antagonist isoforms.

Authors:  W P Arend; C J Guthridge
Journal:  Ann Rheum Dis       Date:  2000-11       Impact factor: 19.103

Review 3.  Ethnic differences in gastric cancer genetic susceptibility: allele flips of interleukin gene.

Authors:  Juwon Kim; Yoonjung Kim; Kyung-A Lee
Journal:  World J Gastroenterol       Date:  2014-04-28       Impact factor: 5.742

4.  A novel genetic polymorphism of inducible nitric oxide synthase is associated with an increased risk of gastric cancer.

Authors:  Jing Shen; Run-Tian Wang; Li-Wei Wang; Yao-Chu Xu; Xin-Ru Wang
Journal:  World J Gastroenterol       Date:  2004-11-15       Impact factor: 5.742

5.  Interleukin-1B and interleukin-1 receptor antagonist gene polymorphisms in Greek multiple sclerosis (MS) patients with bout-onset MS.

Authors:  Konstantinos Aggelakis; Fani Zacharaki; Efthimios Dardiotis; Georgia Xiromerisiou; Vana Tsimourtou; Styliani Ralli; Maria Gkaraveli; Dimitris Bourpoulas; Paraskevi Rodopoulou; Alexandros Papadimitriou; Georgios Hadjigeorgiou
Journal:  Neurol Sci       Date:  2009-10-30       Impact factor: 3.307

6.  Human steroidogenic acute regulatory protein: functional activity in COS-1 cells, tissue-specific expression, and mapping of the structural gene to 8p11.2 and a pseudogene to chromosome 13.

Authors:  T Sugawara; J A Holt; D Driscoll; J F Strauss; D Lin; W L Miller; D Patterson; K P Clancy; I M Hart; B J Clark
Journal:  Proc Natl Acad Sci U S A       Date:  1995-05-23       Impact factor: 11.205

7.  Five genetic markers in the interleukin 1 family in relation to inflammatory bowel disease.

Authors:  P C Stokkers; B E van Aken; N Basoski; P H Reitsma; G N Tytgat; S J van Deventer
Journal:  Gut       Date:  1998-07       Impact factor: 23.059

8.  Positive correlation between interleukin-1 receptor antagonist gene 86bp VNTR polymorphism and colorectal cancer susceptibility: a case-control study.

Authors:  Mostafa Ibrahimi; Maryam Moossavi; Ehsan Nazemalhosseini Mojarad; Mahsa Musavi; Milad Mohammadoo-Khorasani; Zahra Shahsavari
Journal:  Immunol Res       Date:  2019-02       Impact factor: 2.829

9.  Interleukin-1β (IL-1β) & IL-4 gene polymorphisms in patients with systemic lupus erythematosus (SLE) & their association with susceptibility to SLE.

Authors:  Milad Mohammadoo-Khorasani; Saeedeh Salimi; Ehsan Tabatabai; Mahnaz Sandoughi; Zahra Zakeri; Farzaneh Farajian-Mashhadi
Journal:  Indian J Med Res       Date:  2016-05       Impact factor: 2.375

10.  IL1 receptor antagonist gene IL1-RN variable number of tandem repeats polymorphism and cancer risk: a literature review and meta-analysis.

Authors:  Ying Zhang; Changming Liu; Huiping Peng; Jianzhi Zhang; Quanlin Feng
Journal:  PLoS One       Date:  2012-09-25       Impact factor: 3.240

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