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Literature DB >> 843243

Brain-type creatine kinase isoenzyme. Occurrence in serum in acute cerebral disorders.

Abstract

Acute brain damage-cerebrovascular or cardiovascular, traumatic or infectious-released brain-type isoenzyme of creatine kinase (BB-CK) into the circulation within a few hours in 16 of 62 patients (26%). Occurrence of BB-CK was transient in the serum. BB-CK activity was found in the peripheral blood in 13 of 23 patients with diffuse brain damage compared to three of 39 patients with a local cerebrovascular accident (P less than .0005). The mortality of patients having BB-CK in their serum was 63% compared to 39% of those without BB-CK activity in their serum (P less than .05).

Entities: Chemical Disease Species

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Year: 1977 PMID： 843243 DOI： 10.1001/archneur.1977.00500150028004

Source DB: PubMed Journal: Arch Neurol ISSN： 0003-9942

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Cited

10 in total

10. Effect of SNPs on creatine kinase structure and function: identifying potential molecular mechanisms for possible creatine kinase deficiency diseases.

Authors: Chang Li; Qian Zhang; Wei-Jiang Hu; Hang Mu; Zong Lin; Long Ma; Yong-Doo Park; Hai-Meng Zhou
Journal: PLoS One Date: 2012-09-25 Impact factor: 3.240

10 in total

Brain-type creatine kinase isoenzyme. Occurrence in serum in acute cerebral disorders.

Review 1. Blood biologic markers of stroke: improved management, reduced cost?

2. Enzymatic changes in the cerebrospinal fluid as indices of pathological change.

3. Circulating CK-MB and CK-BB isoenzyme after gastrointestinal surgery.

4. Aseptic meningitis and hydrocephalus after posterior fossa surgery.

5. Prognostic value of creatine kinase BB-isoenzyme in high risk newborn infants.

6. Serum creatine kinase B subunit activity in diagnosis of acute myocardial infarction.

7. Immunoelectron microscopic investigation of creatine kinase BB-isoenzyme after cerebral ischemia in gerbils.

8. Creatine kinase BB activity in serum of patients with acute stroke: correlation with the severity of brain damage.

9. Heart type creatine kinase isoenzyme (CK MB) in acute cerebral disorders.

10. Effect of SNPs on creatine kinase structure and function: identifying potential molecular mechanisms for possible creatine kinase deficiency diseases.