Literature DB >> 8431918

t(5;12)(q31;p12). A clinical entity with features of both myeloid leukemia and chronic myelomonocytic leukemia.

J W Wessels1, W E Fibbe, D van der Keur, J E Landegent, D C van der Plas, G J den Ottolander, K J Roozendaal, G C Beverstock.   

Abstract

We report two patients with a myeloproliferative disorder (Philadelphia chromosome-negative chronic myeloid leukemia) and t(5;12)(q31;p12). Until now, only three cases of a translocation (5;12)(q31;p12) have been reported. All investigators had problems classifying their patient's disease into one of the well-defined entities of either MPD or myelodysplastic disorders. We postulate that this translocation may represent a subgroup of patients with features of both chronic myeloid leukemia and chronic myelomonocytic leukemia (CMMoL).

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Mesh:

Year:  1993        PMID: 8431918     DOI: 10.1016/0165-4608(93)90051-m

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN: 0165-4608


  6 in total

1.  Signaling in leukemia: which messenger to kill?

Authors:  W S Pear
Journal:  J Clin Invest       Date:  2000-02       Impact factor: 14.808

2.  Fatal myeloproliferation, induced in mice by TEL/PDGFbetaR expression, depends on PDGFbetaR tyrosines 579/581.

Authors:  M H Tomasson; D W Sternberg; I R Williams; M Carroll; D Cain; J C Aster; R L Ilaria; R A Van Etten; D G Gilliland
Journal:  J Clin Invest       Date:  2000-02       Impact factor: 14.808

Review 3.  New insights in cellular and molecular aspects of BM niche in chronic myelogenous leukemia.

Authors:  Saeid Shahrabi; Shirin Azizidoost; Mohammad Shahjahani; Fakher Rahim; Ahmad Ahmadzadeh; Najmaldin Saki
Journal:  Tumour Biol       Date:  2014-09-19

Review 4.  Chronic myelomonocytic leukemia: Forefront of the field in 2015.

Authors:  Christopher B Benton; Aziz Nazha; Naveen Pemmaraju; Guillermo Garcia-Manero
Journal:  Crit Rev Oncol Hematol       Date:  2015-03-14       Impact factor: 6.312

5.  A Novel IL3-ETV6 Fusion in Chronic Eosinophilic Leukemia Not Otherwise Specified With t(5; 12) (q31; p13): A Case Report and Literature Review.

Authors:  Cenzhu Zhao; Man Wang; Yuchen Zhan; Yang Xu; Suning Chen; Qinrong Wang; Jingnan An; Tianhui Liu
Journal:  Front Oncol       Date:  2022-06-07       Impact factor: 5.738

6.  Order of human hematopoietic growth factor and receptor genes on the long arm of chromosome 5, as determined by fluorescence in situ hybridization.

Authors:  P M Kluck; J Wiegant; A K Raap; H Vrolijk; H J Tanke; R Willemze; J E Landegent
Journal:  Ann Hematol       Date:  1993-01       Impact factor: 3.673

  6 in total

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