BACKGROUND: The Miami modification of the traditional Wertheim-Meigs radical hysterectomy was used to treat Stage IB-IIA cervical cancer in a 25-year prospective study involving 978 patients. METHODS: The modifications included: vaginal reconstruction and closure using bladder and rectosigmoid serosa, retroperitoneal drainage through abdominal suction catheters, and suspension of the denuded ureters with the ipsilateral obliterated hypogastric artery. RESULTS: The overall corrected 5-year survival rate was 90.1%, with a surgical mortality rate of 1.4% and an overall urinary fistula rate of 1.4%. This fistula rate was significantly better than a 4.4% incidence rate in a literature survey. Although not measured, the Miami modification appeared to lengthen the vagina. CONCLUSIONS: Therefore, it was concluded that radical hysterectomy with the Miami modifications can be done safely in most patients with Stage IB-IIA cervical cancer.
BACKGROUND: The Miami modification of the traditional Wertheim-Meigs radical hysterectomy was used to treat Stage IB-IIA cervical cancer in a 25-year prospective study involving 978 patients. METHODS: The modifications included: vaginal reconstruction and closure using bladder and rectosigmoid serosa, retroperitoneal drainage through abdominal suction catheters, and suspension of the denuded ureters with the ipsilateral obliterated hypogastric artery. RESULTS: The overall corrected 5-year survival rate was 90.1%, with a surgical mortality rate of 1.4% and an overall urinary fistula rate of 1.4%. This fistula rate was significantly better than a 4.4% incidence rate in a literature survey. Although not measured, the Miami modification appeared to lengthen the vagina. CONCLUSIONS: Therefore, it was concluded that radical hysterectomy with the Miami modifications can be done safely in most patients with Stage IB-IIA cervical cancer.
Authors: Christine Ellingsen; Ingrid Natvig; Jon-Vidar Gaustad; Kristine Gulliksrud; Tormod A M Egeland; Einar K Rofstad Journal: J Cancer Res Clin Oncol Date: 2009-02-13 Impact factor: 4.553
Authors: Rik Pijpers; Marrije R Buist; Arthur van Lingen; Jan Dijkstra; Paul J van Diest; Gerrit J J Teule; Peter Kenemans; René H M Verheijen Journal: Eur J Nucl Med Mol Imaging Date: 2004-06-25 Impact factor: 9.236
Authors: Alexander Melamed; Daniel J Margul; Ling Chen; Nancy L Keating; Marcela G Del Carmen; Junhua Yang; Brandon-Luke L Seagle; Amy Alexander; Emma L Barber; Laurel W Rice; Jason D Wright; Masha Kocherginsky; Shohreh Shahabi; J Alejandro Rauh-Hain Journal: N Engl J Med Date: 2018-10-31 Impact factor: 91.245
Authors: Alexandre A Jacinto; Marcus S Castilho; Paulo E R S Novaes; Pablo R Novick; Gustavo A Viani; João V Salvajoli; Robson Ferrigno; Antonio Cássio A Pellizzon; Stella S S Lima; Maria A C Maia; Ricardo C Fogaroli Journal: Radiat Oncol Date: 2007-02-22 Impact factor: 3.481