Literature DB >> 843071

[Biosynthesis of rubomycin. The glycosylation of exogenous rubomycin one and carminomycin one by a rubomycin-producing culture].

V I Paranosenkova, V L Karpov.   

Abstract

Production of rubomycin and carminomycinone glycosides by the rubomycin-producing organism was studied with the help of labeled rubomycin and carminomycinone. It was found that both substances were glycoxylized by the rubomycin-producing organism with production of the respective antibiotics. Non-labeled methionine did not decrease incorporation of rubomycinone labeled in the O-methy1 group into rubomycin. It is supposed that the methoxylic group of the latter is incorporated into its structure at early stages of its production, for example at the stage of polyketomethylen. Carminomycinone, which may be considered as desmethylrubomycinone not glycosylated by methylation.

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Year:  1977        PMID: 843071

Source DB:  PubMed          Journal:  Antibiotiki        ISSN: 0003-5637


  3 in total

1.  Intra- and interspecific cosynthetic activity of mutants of Streptomyces coeruleorubidus and Streptomyces galilaeus impaired in the biosynthesis of anthracyclines.

Authors:  M Blumauerová; E Královocová; Z Hostálek; Z Vanĕk
Journal:  Folia Microbiol (Praha)       Date:  1979       Impact factor: 2.099

2.  Biotransformations of anthracyclinones in Streptomyces coeruleorubidus and Streptomyces galilaeus.

Authors:  M Blumauerová; E Královcová; J Matĕjů; J Jizba; Z Vanĕk
Journal:  Folia Microbiol (Praha)       Date:  1979       Impact factor: 2.099

3.  Mutants of Streptomyces coeruleorubidus impaired in the biosynthesis of daunomycinone glycosides and related metabolites.

Authors:  M Blumauerová; K Stajner; V Pokorný; Z Hostálek; Z Vanĕk
Journal:  Folia Microbiol (Praha)       Date:  1978       Impact factor: 2.099

  3 in total

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