Literature DB >> 8429098

The influence of interleukin-2 on vasopressin and oxytocin gene expression in the rodent hypothalamus.

K Pardy1, D Murphy, D Carter, K M Hui.   

Abstract

There is growing evidence of interactions between the central nervous system and the immune system. We present evidence that the cytokine interleukin-2 (IL-2) influences expression of the genes encoding the neuropeptides vasopressin (VP) and oxytocin (OT) in the hypothalamus of the nude mouse. A single injection of recombinant mouse IL-2 (rmIL-2) caused a significant increase in VP and OT mRNA levels in the hypothalamus of nude mice. This effect was specific to the nude mouse. These observations stress the potential value of the nude mouse for studying interactions between the central nervous system (CNS) and the immune system.

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Year:  1993        PMID： 8429098     DOI： 10.1016/0165-5728(93)90002-g

Source DB:  PubMed          Journal:  J Neuroimmunol        ISSN： 0165-5728            Impact factor:   3.478


  6 in total

Review 1.  Immune modulation of the hypothalamic-pituitary-adrenal (HPA) axis during viral infection.

Authors:  Marni N Silverman; Brad D Pearce; Christine A Biron; Andrew H Miller
Journal:  Viral Immunol       Date:  2005       Impact factor: 2.257

2.  Spinal injection of IL-2 or IL-15 alters mechanical and thermal withdrawal thresholds in rats.

Authors:  Juan P Cata; Han-Rong Weng; Patrick M Dougherty
Journal:  Neurosci Lett       Date:  2008-03-29       Impact factor: 3.046

3.  Selective Neuronal and Brain Regional Expession of IL-2 in IL2P 8-GFP Transgenic Mice: Relation to Sensorimotor Gating.

Authors:  Danielle Meola; Zhi Huang; John M Petitto
Journal:  J Alzheimers Dis Parkinsonism       Date:  2013-10-28

4.  A 61-year-old woman develops polyuria after hip revision.

Authors:  Aisha Shaheen; Mark Dobish; Vanessa Gleason; Adam Setren; Jonathan Stem; Benjamin A Kohl
Journal:  J Surg Case Rep       Date:  2016-05-11

5.  Effects of Chronic Social Stress and Maternal Intranasal Oxytocin and Vasopressin on Offspring Interferon-γ and Behavior.

Authors:  Christopher A Murgatroyd; Alexandria Hicks-Nelson; Alexandria Fink; Gillian Beamer; Kursat Gurel; Fawzy Elnady; Florent Pittet; Benjamin C Nephew
Journal:  Front Endocrinol (Lausanne)       Date:  2016-12-14       Impact factor: 5.555

Review 6.  Nonsocial functions of hypothalamic oxytocin.

Authors:  Hai-Peng Yang; Liwei Wang; Liqun Han; Stephani C Wang
Journal:  ISRN Neurosci       Date:  2013-07-07
  6 in total

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