Literature DB >> 8428942

Domain structure of an N-ethylmaleimide-sensitive fusion protein involved in vesicular transport.

M Tagaya1, D W Wilson, M Brunner, N Arango, J E Rothman.   

Abstract

N-Ethylmaleimide-sensitive fusion protein (NSF) is an essential component for protein transport between Golgi cisternae. Sequence analysis and proteolytic dissection reveal that NSF contains two tandem "ATP domains," each containing the consensus sequence for the binding of nucleotide. When Escherichia coli-produced Chinese hamster ovary NSF is purified, it exhibits a low, but significant, ATPase activity. The ATPase activity of NSF is sensitive to N-ethylmaleimide and influenced by monoclonal antibodies against recombinant NSF.

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Year:  1993        PMID: 8428942

Source DB:  PubMed          Journal:  J Biol Chem        ISSN: 0021-9258            Impact factor:   5.157


  55 in total

1.  Structural characterization of full-length NSF and 20S particles.

Authors:  Lei-Fu Chang; Song Chen; Cui-Cui Liu; Xijiang Pan; Jiansen Jiang; Xiao-Chen Bai; Xin Xie; Hong-Wei Wang; Sen-Fang Sui
Journal:  Nat Struct Mol Biol       Date:  2012-02-05       Impact factor: 15.369

2.  Cleavage of rabaptin-5 blocks endosome fusion during apoptosis.

Authors:  S C Cosulich; H Horiuchi; M Zerial; P R Clarke; P G Woodman
Journal:  EMBO J       Date:  1997-10-15       Impact factor: 11.598

3.  Asymmetric accumulation of hippocampal 7S SNARE complexes occurs regardless of kindling paradigm.

Authors:  Elena A Matveeva; Thomas C Vanaman; Sidney W Whiteheart; John T Slevin
Journal:  Epilepsy Res       Date:  2006-12-14       Impact factor: 3.045

Review 4.  Exocytosis in plants.

Authors:  G Thiel; N Battey
Journal:  Plant Mol Biol       Date:  1998-09       Impact factor: 4.076

5.  Arrangement of subunits in 20 S particles consisting of NSF, SNAPs, and SNARE complexes.

Authors:  T M Hohl; F Parlati; C Wimmer; J E Rothman; T H Söllner; H Engelhardt
Journal:  Mol Cell       Date:  1998-11       Impact factor: 17.970

Review 6.  Requirements for the catalytic cycle of the N-ethylmaleimide-Sensitive Factor (NSF).

Authors:  Chunxia Zhao; Everett C Smith; Sidney W Whiteheart
Journal:  Biochim Biophys Acta       Date:  2011-06-13

Review 7.  The protein machinery of vesicle budding and fusion.

Authors:  J E Rothman
Journal:  Protein Sci       Date:  1996-02       Impact factor: 6.725

8.  The soluble N-ethylmaleimide-sensitive factor attached protein receptor complex in growth cones: molecular aspects of the axon terminal development.

Authors:  M Igarashi; M Tagaya; Y Komiya
Journal:  J Neurosci       Date:  1997-02-15       Impact factor: 6.167

9.  Three αSNAP and 10 ATP molecules are used in SNARE complex disassembly by N-ethylmaleimide-sensitive factor (NSF).

Authors:  Niket Shah; Karen N Colbert; Michael D Enos; Daniel Herschlag; William I Weis
Journal:  J Biol Chem       Date:  2014-12-09       Impact factor: 5.157

10.  N-Ethylmaleimide-Sensitive Factor b (nsfb) Is Required for Normal Pigmentation of the Zebrafish Retinal Pigment Epithelium.

Authors:  Nicholas J Hanovice; Christina M S Daly; Jeffrey M Gross
Journal:  Invest Ophthalmol Vis Sci       Date:  2015-11       Impact factor: 4.799

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