Literature DB >> 8428519

The fibroblast growth factor receptor 3 gene (FGFR3) is assigned to human chromosome 4.

K Keegan1, L Rooke, M Hayman, N K Spurr.   

Abstract

Fibroblast growth factor receptors (FGFRs) have recently been isolated and shown to be transmembrane tyrosine kinase receptors. The FGFR1 gene has previously been assigned to human chromosome 8 and the FGFR4 gene to human chromosome 5. Here we demonstrate, by using somatic cell hybrids, that the FGFR3 gene localizes to human chromosome 4, showing that it, too, resides on a chromosome distinct from those on which other FGFRs have been localized.

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Year:  1993        PMID: 8428519     DOI: 10.1159/000133465

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN: 0301-0171


  5 in total

Review 1.  Growth factors in glioma angiogenesis: FGFs, PDGF, EGF, and TGFs.

Authors:  I F Dunn; O Heese; P M Black
Journal:  J Neurooncol       Date:  2000 Oct-Nov       Impact factor: 4.130

2.  Novel and Recurrent Mutations in the FGFR3 Gene and Double Heterozygosity Cases in a Cohort of Brazilian Patients with Skeletal Dysplasia.

Authors:  Maria E S Gomes; Thatiane Y Kanazawa; Fernanda R Riba; Natálya G Pereira; Maria C C Zuma; Natana C Rabelo; Maria T Sanseverino; Dafne D G Horovitz; Juan C Llerena; Denise P Cavalcanti; Sayonara Gonzalez
Journal:  Mol Syndromol       Date:  2018-02-02

3.  Prenatal diagnosis of skeletal dysplasia due to FGFR3 gene mutations: a 9-year experience : prenatal diagnosis in FGFR3 gene.

Authors:  M J Trujillo-Tiebas; M Fenollar-Cortés; I Lorda-Sánchez; J Díaz-Recasens; A Carrillo Redondo; C Ramos-Corrales; C Ayuso
Journal:  J Assist Reprod Genet       Date:  2009-09-30       Impact factor: 3.412

4.  Hypochondroplasia in a child with 1620C>G (Asn540Lys) mutation in FGFR3.

Authors:  Hüseyin Anıl Korkmaz; Filiz Hazan; Ceyhun Dizdarer; Ajlan Tükün
Journal:  J Clin Res Pediatr Endocrinol       Date:  2012-11-12

5.  FGFR3 mutation frequency in 324 cases from the International Skeletal Dysplasia Registry.

Authors:  Yuan Xue; Angela Sun; P Betty Mekikian; Jorge Martin; David L Rimoin; Ralph S Lachman; William R Wilcox
Journal:  Mol Genet Genomic Med       Date:  2014-08-05       Impact factor: 2.183

  5 in total

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