Literature DB >> 8427387

Prevalence of cutaneous leishmaniasis along the Nile River north of Khartoum (Sudan) in the aftermath of an epidemic in 1985.

A Y Kadaro1, H W Ghalib, M S Ali, I Eltoum, A Ismail, A Gaafar, M Kemp, A A Kordofani, S G Reed, A M el-Hassan.   

Abstract

Based on a pilot clinical study of the prevalence of cutaneous leishmaniasis (CL) among school children in villages on both banks of the Nile River north of Khartoum, Sudan in the aftermath of a 1985 epidemic, we studied a random sample (303 individuals) from one of these villages to determine the prevalence of infection and exposure to CL. Four percent of the population had active CL lesions, 47% had healed lesions, and another 43% reacted positively to sensitization with leishmanin in the absence of past or active CL lesions. Ninety-one percent of the total population reacted positively to leishmanin. The present status of CL in the area and possible reasons for the emergence of the epidemic are discussed, and gaps in our knowledge about the epidemic are identified.

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Year:  1993        PMID: 8427387     DOI: 10.4269/ajtmh.1993.48.44

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN: 0002-9637            Impact factor:   2.345


  5 in total

1.  Leishmanin skin test lymphoproliferative responses and cytokine production after symptomatic or asymptomatic Leishmania major infection in Tunisia.

Authors:  A Sassi; H Louzir; A Ben Salah; M Mokni; A Ben Osman; K Dellagi
Journal:  Clin Exp Immunol       Date:  1999-04       Impact factor: 4.330

2.  Antigen-presenting cells in human cutaneous leishmaniasis due to Leishmania major.

Authors:  A M ElHassan; A Gaafar; T G Theander
Journal:  Clin Exp Immunol       Date:  1995-03       Impact factor: 4.330

3.  Dichotomy of the human T cell response to Leishmania antigens. I. Th1-like response to Leishmania major promastigote antigens in individuals recovered from cutaneous leishmaniasis.

Authors:  M Kemp; A S Hey; J A Kurtzhals; C B Christensen; A Gaafar; M D Mustafa; A A Kordofani; A Ismail; A Kharazmi; T G Theander
Journal:  Clin Exp Immunol       Date:  1994-06       Impact factor: 4.330

4.  Dichotomy of the T cell response to Leishmania antigens in patients suffering from cutaneous leishmaniasis; absence or scarcity of Th1 activity is associated with severe infections.

Authors:  A Gaafar; A Kharazmi; A Ismail; M Kemp; A Hey; C B Christensen; M Dafalla; A Y el Kadaro; A M el Hassan; T G Theander
Journal:  Clin Exp Immunol       Date:  1995-05       Impact factor: 4.330

5.  Uncharted territory of the epidemiological burden of cutaneous leishmaniasis in sub-Saharan Africa-A systematic review.

Authors:  Temmy Sunyoto; Kristien Verdonck; Sayda El Safi; Julien Potet; Albert Picado; Marleen Boelaert
Journal:  PLoS Negl Trop Dis       Date:  2018-10-25
  5 in total

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