Literature DB >> 8426087

Immunotherapy of tularemia: characterization of a monoclonal antibody reactive with Francisella tularensis.

R B Narayanan1, J J Drabick, J C Williams, A H Fortier, M S Meltzer, J C Sadoff, C R Bolt, C A Nacy.   

Abstract

An IgM monoclonal antibody (mAb) recognized surface antigens specific to Francisella tularensis wild-type (Schu4) and live vaccine strain (LVS), and reacted with both in ELISA and slide agglutination tests. This mAb also reacted with LVS microorganisms in tissues of infected mice as assessed by an indirect fluorescence technique. Western blot analysis showed the mAb to react with antigens associated with F. tularensis LPS.

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Year:  1993        PMID： 8426087     DOI： 10.1002/jlb.53.1.112

Source DB:  PubMed          Journal:  J Leukoc Biol        ISSN： 0741-5400            Impact factor:   4.962


  8 in total

1.  Structural and immunochemical characterization of the lipooligosaccharides expressed by Neisseria subflava 44.

Authors:  Y Tong; V Reinhold; B Reinhold; B Brandt; D C Stein
Journal:  J Bacteriol       Date:  2001-02       Impact factor: 3.490

2.  Antibodies contribute to effective vaccination against respiratory infection by type A Francisella tularensis strains.

Authors:  Gopi Mara-Koosham; Julie A Hutt; C Rick Lyons; Terry H Wu
Journal:  Infect Immun       Date:  2011-01-31       Impact factor: 3.441

3.  Growth of Francisella tularensis LVS in macrophages: the acidic intracellular compartment provides essential iron required for growth.

Authors:  A H Fortier; D A Leiby; R B Narayanan; E Asafoadjei; R M Crawford; C A Nacy; M S Meltzer
Journal:  Infect Immun       Date:  1995-04       Impact factor: 3.441

4.  Characterization of monoclonal antibodies to terminal and internal O-antigen epitopes of Francisella tularensis lipopolysaccharide.

Authors:  Marly I Roche; Zhaohua Lu; Julia H Hui; Jacqueline Sharon
Journal:  Hybridoma (Larchmt)       Date:  2011-02

5.  Purified lipopolysaccharide from Francisella tularensis live vaccine strain (LVS) induces protective immunity against LVS infection that requires B cells and gamma interferon.

Authors:  V C Dreisbach; S Cowley; K L Elkins
Journal:  Infect Immun       Date:  2000-04       Impact factor: 3.441

6.  Generation and characterization of hybridoma antibodies for immunotherapy of tularemia.

Authors:  Zhaohua Lu; Marly I Roche; Julia H Hui; Berkay Unal; Philip L Felgner; Sunita Gulati; Guillermo Madico; Jacqueline Sharon
Journal:  Immunol Lett       Date:  2007-08-08       Impact factor: 3.685

7.  Immunological and molecular characterization of three variant subtype P1.14 strains of Neisseria meningitidis.

Authors:  N B Saunders; B L Brandt; R L Warren; B D Hansen; W D Zollinger
Journal:  Infect Immun       Date:  1998-07       Impact factor: 3.441

8.  The binding sites of monoclonal antibodies to the non-reducing end of Francisella tularensis O-antigen accommodate mainly the terminal saccharide.

Authors:  Zhaohua Lu; Michael J Rynkiewicz; Chiou-Ying Yang; Guillermo Madico; Hillary M Perkins; Qi Wang; Catherine E Costello; Joseph Zaia; Barbara A Seaton; Jacqueline Sharon
Journal:  Immunology       Date:  2013-11       Impact factor: 7.397
  8 in total

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