Literature DB >> 8424773

Characterization of the functional domain of tissue inhibitor of metalloproteinases-2 (TIMP-2).

Y A DeClerck1, T D Yean, Y Lee, J M Tomich, K E Langley.   

Abstract

Analysis of the functional domain of tissue inhibitor of metallo-proteinases-2 (TIMP-2) was performed using limited proteolytic degradation with trypsin. This treatment generated a 13.5 kDa fragment which was purified and shown to consist of an uncleaved N-terminal region extending from residue 1 to residue 132. The fragment retains the ability to inhibit activated interstitial collagenase and to block the autocatalytic activation of procollagenase.

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Year:  1993        PMID： 8424773      PMCID： PMC1132131          DOI： 10.1042/bj2890065

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  30 in total

1.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

2.  A quantitative collagen film collagenase assay for large numbers of samples.

Authors:  B Johnson-Wint
Journal:  Anal Biochem       Date:  1980-05-01       Impact factor: 3.365

3.  Primary structure and cDNA cloning of human fibroblast collagenase inhibitor.

Authors:  D F Carmichael; A Sommer; R C Thompson; D C Anderson; C G Smith; H G Welgus; G P Stricklin
Journal:  Proc Natl Acad Sci U S A       Date:  1986-04       Impact factor: 11.205

4.  Fragments of human fibroblast collagenase. Purification and characterization.

Authors:  I M Clark; T E Cawston
Journal:  Biochem J       Date:  1989-10-01       Impact factor: 3.857

5.  Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP-2.

Authors:  G I Goldberg; B L Marmer; G A Grant; A Z Eisen; S Wilhelm; C S He
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

6.  Extracts of human articular cartilage contain an inhibitor of tissue metalloproteinases.

Authors:  D D Dean; J F Woessner
Journal:  Biochem J       Date:  1984-02-15       Impact factor: 3.857

7.  Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity.

Authors:  A J Docherty; A Lyons; B J Smith; E M Wright; P E Stephens; T J Harris; G Murphy; J J Reynolds
Journal:  Nature       Date:  1985 Nov 7-13       Impact factor: 49.962

8.  An inhibitor of collagenase from human amniotic fluid. Purification, characterization and action on metalloproteinases.

Authors:  G Murphy; T E Cawston; J J Reynolds
Journal:  Biochem J       Date:  1981-04-01       Impact factor: 3.857

9.  Purification of rabbit bone inhibitor of collagenase.

Authors:  T E Cawston; W A Galloway; E Mercer; G Murphy; J J Reynolds
Journal:  Biochem J       Date:  1981-04-01       Impact factor: 3.857

10.  Human skin fibroblast collagenase inhibitor. Purification and biochemical characterization.

Authors:  G P Stricklin; H G Welgus
Journal:  J Biol Chem       Date:  1983-10-25       Impact factor: 5.157
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  7 in total

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Authors:  L Bányai; L Patthy
Journal:  Protein Sci       Date:  1999-08       Impact factor: 6.725

Review 2.  Collagenase and surgical disease.

Authors:  Timothy R Donahue; Jonathan R Hiatt; Ronald W Busuttil
Journal:  Hernia       Date:  2006-12       Impact factor: 4.739

Review 3.  Matrix metalloproteinase inhibitors: present achievements and future prospects.

Authors:  L J Denis; J Verweij
Journal:  Invest New Drugs       Date:  1997       Impact factor: 3.850

4.  An integrin-binding N-terminal peptide region of TIMP-2 retains potent angio-inhibitory and anti-tumorigenic activity in vivo.

Authors:  Dong-Wan Seo; W Carl Saxinger; Liliana Guedez; Anna Rita Cantelmo; Adriana Albini; William G Stetler-Stevenson
Journal:  Peptides       Date:  2011-08-16       Impact factor: 3.750

5.  Identification, purification and partial characterization of tissue inhibitor of matrix metalloproteinase-2 in bovine pulmonary artery smooth muscle.

Authors:  Malay Mandal; Amritlal Mandal; Sudip Das; Tapati Chakraborti; Sajal Chakraborti
Journal:  Mol Cell Biochem       Date:  2003-12       Impact factor: 3.396

6.  Matrix metalloproteinase-10/TIMP-2 structure and analyses define conserved core interactions and diverse exosite interactions in MMP/TIMP complexes.

Authors:  Jyotica Batra; Alexei S Soares; Christine Mehner; Evette S Radisky
Journal:  PLoS One       Date:  2013-09-20       Impact factor: 3.240

7.  TIMPs of parasitic helminths - a large-scale analysis of high-throughput sequence datasets.

Authors:  Cinzia Cantacessi; Andreas Hofmann; Darren Pickering; Severine Navarro; Makedonka Mitreva; Alex Loukas
Journal:  Parasit Vectors       Date:  2013-05-30       Impact factor: 3.876
  7 in total

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