[A field study of the efficacy of ivermectin in propylene glycol in the treatment of mange in guinea pigs].

The clinical manifestation of mange in a guinea-pig population in Utrecht is discussed. The etiology and the treatment with two subcutaneous injections of ivermectin 0.2 mg/kg with a ten-day interval, is described. A total of 37 guinea-pigs with symptoms and 36 guinea-pig without signs of mange were treated. On the 21st day all previously infested guinea-pigs were free of symptoms. During this study side-effects occurred in 11 of the 73 animals. The most prominent side-effects were a (sub-)dermal necrosis in the younger animals and an inflammation of the cutis in the older animals. The side-effects were probably caused by propylene glycol which was used as a diluent.