Literature DB >> 8421184

Ceftriaxone no longer predictably cures chancroid in Kenya.

M Tyndall1, M Malisa, F A Plummer, J Ombetti, J O Ndinya-Achola, A R Ronald.   

Abstract

Ceftriaxone in a dose of 250 mg given intramuscularly is currently recommended for the treatment of chancroid. Among 133 men in Nairobi, Kenya, with culture-proven chancroid, who were treated with ceftriaxone, treatment failed in 35%. Poor outcome was associated with human immunodeficiency virus type 1 seropositivity. Thus, treatment recommendations for chancroid should be reevaluated.

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Year:  1993        PMID: 8421184     DOI: 10.1093/infdis/167.2.469

Source DB:  PubMed          Journal:  J Infect Dis        ISSN: 0022-1899            Impact factor:   5.226


  6 in total

Review 1.  Diagnostic tests for chancroid.

Authors:  D A Lewis
Journal:  Sex Transm Infect       Date:  2000-04       Impact factor: 3.519

2.  Emergence of Haemophilus ducreyi resistance to trimethoprim-sulfamethoxazole in Rwanda.

Authors:  E Van Dyck; J Bogaerts; H Smet; W M Tello; V Mukantabana; P Piot
Journal:  Antimicrob Agents Chemother       Date:  1994-07       Impact factor: 5.191

Review 3.  Chancroid: clinical manifestations, diagnosis, and management.

Authors:  D A Lewis
Journal:  Sex Transm Infect       Date:  2003-02       Impact factor: 3.519

Review 4.  Chancroid and Haemophilus ducreyi: an update.

Authors:  D L Trees; S A Morse
Journal:  Clin Microbiol Rev       Date:  1995-07       Impact factor: 26.132

5.  Inducible immunity with a pilus preparation booster vaccination in an animal model of Haemophilus ducreyi infection and disease.

Authors:  M Desjardins; L G Filion; S Robertson; D W Cameron
Journal:  Infect Immun       Date:  1995-05       Impact factor: 3.441

6.  A (p)ppGpp-null mutant of Haemophilus ducreyi is partially attenuated in humans due to multiple conflicting phenotypes.

Authors:  Concerta Holley; Dharanesh Gangaiah; Wei Li; Kate R Fortney; Diane M Janowicz; Sheila Ellinger; Beth Zwickl; Barry P Katz; Stanley M Spinola
Journal:  Infect Immun       Date:  2014-06-09       Impact factor: 3.441

  6 in total

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