Literature DB >> 841620

Synthesis of new steroid haptens for radioimmunoassay. Part III. 15beta-Carboxyethylmercaptosteroid-bovine serum albumin conjugates. Specific antisera for radioimmunoassay of 5alpha-dihydrotestosterone, 5alpha-androstane-3beta, 17beta-diol and 5alpha-androstane-3alpha, 17beta-diol.

P N Rao, A H Khan, P H Moore.   

Abstract

The syntheses of 15beta-carboxyethylmercapto-5alpha-dihydrotestosterone, 15beta-carbosyethylmercapto-5alpha-androstane-3beta, 17beta-diol and 15beta-carboxyethylmercapto-5alpha-androstane-3alpha, 17beta-diol and the preparation of their bovine serum albumin (BSA) conjugates are described. These conjugates were employed for the generation of specific antisera suitable for radioimmunoassay (RIA) of 5alpha-dihydrotestosterone (5alpha-DHT), 5alpha-androstane-3beta, 17beta-diol (3beta-diol) and 5alpha-androstane-3alpha, 17beta-diol (3alpha-diol).

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Year:  1977        PMID： 841620     DOI： 10.1016/0039-128x(77)90037-x

Source DB:  PubMed          Journal:  Steroids        ISSN： 0039-128X            Impact factor:   2.668


  5 in total

1.  The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men.

Authors:  Kishore M Lakshman; Beth Kaplan; Thomas G Travison; Shehzad Basaria; Philip E Knapp; Atam B Singh; Michael P LaValley; Norman A Mazer; Shalender Bhasin
Journal:  J Clin Endocrinol Metab       Date:  2010-06-09       Impact factor: 5.958

2.  Urinary unconjugated 5 alpha-androstane-3 alpha, 17 beta-diol in patients with prostatic tumours.

Authors:  C M Puah; G Williams; R Ghanadian
Journal:  Urol Res       Date:  1982

3.  Androgen administration to aged male mice increases anti-anxiety behavior and enhances cognitive performance.

Authors:  Cheryl A Frye; Kassandra Edinger; Kanako Sumida
Journal:  Neuropsychopharmacology       Date:  2007-07-11       Impact factor: 7.853

4.  Does place of birth influence endogenous hormone levels in Asian-American women?

Authors:  R T Falk; T R Fears; R N Hoover; M C Pike; A H Wu; A M Y Nomura; L N Kolonel; D W West; R G Ziegler
Journal:  Br J Cancer       Date:  2002-07-01       Impact factor: 7.640

5.  Learning and the Lifespan: What's Sex Got to Do With It?

Authors:  Amy Stave Kohtz; Cheryl A Frye
Journal:  Front Neurosci       Date:  2020-03-20       Impact factor: 4.677
  5 in total

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