Literature DB >> 8416057

Regional cerebral blood flow during experimental phobic fear.

M Fredrikson1, G Wik, T Greitz, L Eriksson, S Stone-Elander, K Ericson, G Sedvall.   

Abstract

Positron emission tomographic measurements of regional cerebral blood flow (rCBF) were used to investigate central nervous system correlates of fear and anxiety. Volunteers with symptomatic snake phobia were studied while exposed to visual phobogenic, aversive, and neutral stimuli. Anxiety ratings and the number of nonspecific electrodermal fluctuations increased as a function of phobic stimulation. Phobic, compared to neutral and aversive, stimulation elevated rCBF in the visual associative cortex. The basal ganglia were not activated more by phobic than aversive or neutral stimulation. However, cortical and thalamic rCBF were always correlated during phobic but not aversive or neutral stimulation. This indicates that the thalamus could be a relay station for phobic stimulus processing and affect.

Entities:  

Mesh：

Year:  1993        PMID： 8416057     DOI： 10.1111/j.1469-8986.1993.tb03211.x

Source DB:  PubMed          Journal:  Psychophysiology        ISSN： 0048-5772            Impact factor:   4.016


  15 in total

1.  Explicit and implicit neural mechanisms for processing of social information from facial expressions: a functional magnetic resonance imaging study.

Authors:  H Critchley; E Daly; M Phillips; M Brammer; E Bullmore; S Williams; T Van Amelsvoort; D Robertson; A David; D Murphy
Journal:  Hum Brain Mapp       Date:  2000-02       Impact factor: 5.038

Review 2.  The current status of research on the structure of evaluative space.

Authors:  Catherine J Norris; Jackie Gollan; Gary G Berntson; John T Cacioppo
Journal:  Biol Psychol       Date:  2010-03-24       Impact factor: 3.251

3.  Neurocognitive effects of phobia-related stimuli in animal-fearful individuals.

Authors:  Bruno Kopp; René Altmann
Journal:  Cogn Affect Behav Neurosci       Date:  2005-12       Impact factor: 3.282

4.  Attention and amygdala activity: an fMRI study with spider pictures in spider phobia.

Authors:  Georg W Alpers; Antje B M Gerdes; Bernadette Lagarie; Katharina Tabbert; Dieter Vaitl; Rudolf Stark
Journal:  J Neural Transm (Vienna)       Date:  2008-08-26       Impact factor: 3.575

5.  Amygdala activity at encoding correlated with long-term, free recall of emotional information.

Authors:  L Cahill; R J Haier; J Fallon; M T Alkire; C Tang; D Keator; J Wu; J L McGaugh
Journal:  Proc Natl Acad Sci U S A       Date:  1996-07-23       Impact factor: 11.205

6.  Brain systems underlying encounter expectancy bias in spider phobia.

Authors:  Tatjana Aue; Marie-Eve Hoeppli; Camille Piguet; Christoph Hofstetter; Sebastian W Rieger; Patrik Vuilleumier
Journal:  Cogn Affect Behav Neurosci       Date:  2015-06       Impact factor: 3.282

7.  Effect of acute psychological stress on prefrontal GABA concentration determined by proton magnetic resonance spectroscopy.

Authors:  Gregor Hasler; Jan Willem van der Veen; Christian Grillon; Wayne C Drevets; Jun Shen
Journal:  Am J Psychiatry       Date:  2010-07-15       Impact factor: 18.112

Review 8.  Mapping brain function in freely moving subjects.

Authors:  Daniel P Holschneider; Jean-Michel I Maarek
Journal:  Neurosci Biobehav Rev       Date:  2004-09       Impact factor: 8.989

9.  Emotional blunting following left basal ganglia stroke: the role of depression and fronto-limbic functional alterations.

Authors:  Sergio Paradiso; Katharine Ostedgaard; Jatin Vaidya; Laura Boles Ponto; Robert Robinson
Journal:  Psychiatry Res       Date:  2012-11-21       Impact factor: 3.222

10.  A review of neuroimaging studies of anxiety disorders in China.

Authors:  Jing Chen; Shenxun Shi
Journal:  Neuropsychiatr Dis Treat       Date:  2011-05-02       Impact factor: 2.570
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.