Neonatal and infant heart transplantation.

Since the advent of cyclosporine A, cardiac transplantation has been offered routinely for adolescents and children with cardiomyopathy refractory to medical management. Recently, cardiac transplantation has been offered to neonates with severe structural congenital heart disease. This article reviews the indications, pretransplant evaluation, and post-transplant management of neonates and infants undergoing cardiac transplantation.