Literature DB >> 8411396

Herpes simplex virus thymidine kinase and specific stages of latency in murine trigeminal ganglia.

J G Jacobson1, K L Ruffner, M Kosz-Vnenchak, C B Hwang, K K Wobbe, D M Knipe, D M Coen.   

Abstract

From marker rescue, sequencing, transcript, and latency analyses of the thymidine kinase-negative herpes simplex virus mutant dlsactk and studies using the thymidine kinase inhibitor Ro 31-5140, we infer that the virus-encoded thymidine kinase is required in murine trigeminal ganglia for acute replication and lytic gene expression, for increasing the numbers of cells expressing latency-associated transcripts, and for reactivation from latent infection.

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Year:  1993        PMID： 8411396      PMCID： PMC238141     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  47 in total

1.  A genetic approach to promoter recognition during trans induction of viral gene expression.

Authors:  D M Coen; S P Weinheimer; S L McKnight
Journal:  Science       Date:  1986-10-03       Impact factor: 47.728

2.  The association of herpes simplex virus with squamous carcinoma of the cervix, and studies of the virus thymidine kinase gene.

Authors:  N M Wilkie; R P Eglin; P G Sanders; J B Clements
Journal:  Proc R Soc Lond B Biol Sci       Date:  1980-11-19

3.  Unusual regulation of expression of the herpes simplex virus DNA polymerase gene.

Authors:  K K Wobbe; P Digard; D Staknis; D M Coen
Journal:  J Virol       Date:  1993-09       Impact factor: 5.103

4.  In vitro and in vivo transcription initiation sites on the TK-encoding BamHI Q fragment of HSV-1 DNA.

Authors:  G S Read; J A Sharp; W C Summers
Journal:  Virology       Date:  1984-10-30       Impact factor: 3.616

5.  Herpes simplex virus thymidine kinase expression in trigeminal ganglion infection: correlation of enzyme activity with ganglion virus titer and evidence of in vivo complementation.

Authors:  R B Tenser; S Ressel; M E Dunstan
Journal:  Virology       Date:  1981-07-15       Impact factor: 3.616

6.  Thymidine kinase (TK) activity in herpes simplex virus type 1 recombinants that carry insertions affecting regulation of the TK gene.

Authors:  R B Tenser; W A Edris
Journal:  Virology       Date:  1986-11       Impact factor: 3.616

7.  Immunity in the female genital tract after intravaginal vaccination of mice with an attenuated strain of herpes simplex virus type 2.

Authors:  M R McDermott; J R Smiley; P Leslie; J Brais; H E Rudzroga; J Bienenstock
Journal:  J Virol       Date:  1984-09       Impact factor: 5.103

8.  Resistance of peripheral autonomic neurons to in vivo productive infection by herpes simplex virus mutants deficient in thymidine kinase activity.

Authors:  R W Price; A Khan
Journal:  Infect Immun       Date:  1981-11       Impact factor: 3.441

9.  Establishment of latency in mice by herpes simplex virus 1 recombinants that carry insertions affecting regulation of the thymidine kinase gene.

Authors:  A E Sears; B Meignier; B Roizman
Journal:  J Virol       Date:  1985-08       Impact factor: 5.103

10.  A low thymidine kinase-producing mutant of herpes simplex virus type 1 causes latent trigeminal ganglia infections in mice.

Authors:  Y Gordon; D H Gilden; Y Shtram; Y Asher; E Tabor; M Wellish; M Devlin; D Snipper; J Hadar; Y Becker
Journal:  Arch Virol       Date:  1983       Impact factor: 2.574
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  24 in total

1.  Infection of human NT2 cells and differentiated NT-neurons with herpes simplex virus and replication-incompetent herpes simplex virus vectors.

Authors:  J P Weir
Journal:  J Neurovirol       Date:  2001-02       Impact factor: 2.643

2.  Failure of thymidine kinase-negative herpes simplex virus to reactivate from latency following efficient establishment.

Authors:  Shih-Heng Chen; Angela Pearson; Donald M Coen; Shun-Hua Chen
Journal:  J Virol       Date:  2004-01       Impact factor: 5.103

Review 3.  Resistance of herpes simplex viruses to nucleoside analogues: mechanisms, prevalence, and management.

Authors:  Jocelyne Piret; Guy Boivin
Journal:  Antimicrob Agents Chemother       Date:  2010-11-15       Impact factor: 5.191

4.  Characterization of herpes simplex virus type 1 thymidine kinase mutants selected under a single round of high-dose brivudin.

Authors:  Graciela Andrei; Jan Balzarini; Pierre Fiten; Erik De Clercq; Ghislain Opdenakker; Robert Snoeck
Journal:  J Virol       Date:  2005-05       Impact factor: 5.103

5.  Herpes simplex virus DNA synthesis is not a decisive regulatory event in the initiation of lytic viral protein expression in neurons in vivo during primary infection or reactivation from latency.

Authors:  N M Sawtell; R L Thompson; R L Haas
Journal:  J Virol       Date:  2006-01       Impact factor: 5.103

6.  The latent herpes simplex virus type 1 genome copy number in individual neurons is virus strain specific and correlates with reactivation.

Authors:  N M Sawtell; D K Poon; C S Tansky; R L Thompson
Journal:  J Virol       Date:  1998-07       Impact factor: 5.103

7.  Phosphorylation of herpes simplex virus 1 dUTPase regulates viral virulence and genome integrity by compensating for low cellular dUTPase activity in the central nervous system.

Authors:  Akihisa Kato; Jun Arii; Yoshio Koyanagi; Yasushi Kawaguchi
Journal:  J Virol       Date:  2014-10-15       Impact factor: 5.103

8.  Phosphorylation of a herpes simplex virus 1 dUTPase by a viral protein kinase, Us3, dictates viral pathogenicity in the central nervous system but not at the periphery.

Authors:  Akihisa Kato; Keiko Shindo; Yuhei Maruzuru; Yasushi Kawaguchi
Journal:  J Virol       Date:  2013-12-18       Impact factor: 5.103

9.  Correlation between precolonization of trigeminal ganglia by attenuated strains of pseudorabies virus and resistance to wild-type virus latency.

Authors:  L M Schang; G F Kutish; F A Osorio
Journal:  J Virol       Date:  1994-12       Impact factor: 5.103

10.  Diverse herpes simplex virus type 1 thymidine kinase mutants in individual human neurons and Ganglia.

Authors:  Kening Wang; Gowtham Mahalingam; Susan E Hoover; Erik K Mont; Steven M Holland; Jeffrey I Cohen; Stephen E Straus
Journal:  J Virol       Date:  2007-04-25       Impact factor: 5.103
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