Literature DB >> 841104

The effect of prostaglandin E2 on the cardiovascular response to angiotensin II in pregnant rabbits.

P M O'Brien, G M Filshie, F Broughton Pipkin.   

Abstract

The rise in arterial blood pressure in response to angiotensin II was studied in the last third of pregnancy in rabbits. The response was compared with that of pregnant rabbits during infusion of prostaglandin E2 and F2alpha. Prostaglandin E2 significantly diminished the rise in diastolic pressure in response to angiotensin II. Prostaglandin F2alpha did not alter the response. Intravenous indomethacin elevated the blood pressure and caused an absolute increase in the pressor response. It did not mediate a change in the percentage rise in blood pressure in response to angiotensin II.

Entities:  

Mesh：

Substances：

Year:  1977        PMID： 841104     DOI： 10.1016/0090-6980(77)90054-5

Source DB:  PubMed          Journal:  Prostaglandins        ISSN： 0090-6980


  3 in total

Review 1.  Aetiology of pre-eclampsia: a review.

Authors:  E M Symonds
Journal:  J R Soc Med       Date:  1980-12       Impact factor: 5.344

2.  The effect of dietary supplementation with linoleic and gammalinolenic acids on the pressor response to angiotensin II--a possible role in pregnancy-induced hypertension?

Authors:  P M O'Brien; R Morrison; F Broughton Pipkin
Journal:  Br J Clin Pharmacol       Date:  1985-03       Impact factor: 4.335

3.  The effects of deprivation of prostaglandin precursors on vascular sensitivity to angiotensin II and on the kidney in the pregnant rabbit.

Authors:  P M O'Brien; F Broughton Pipkin
Journal:  Br J Pharmacol       Date:  1979-01       Impact factor: 8.739
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.