| Literature DB >> 8410512 |
F Bortolotti1, C Crivellaro, M R Brunetto, P Cadrobbi, A Bertolini, A Alberti.
Abstract
A 14-year-old girl with chronic hepatitis B had seroconversion from hepatitis B e antigen to antibody and achieved biochemical remission after 2 years. The disease reactivated 9 years later when a precore mutant had become the prevalent hepatitis B virus strain in serum. These results suggest that selection of a precore mutant might induce reactivation during adult life of chronic hepatitis B acquired in childhood, thus worsening the prognosis.Entities:
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Year: 1993 PMID： 8410512 DOI： 10.1016/s0022-3476(05)80956-4
Source DB: PubMed Journal: J Pediatr ISSN： 0022-3476 Impact factor: 4.406