OBJECTIVE: Validation of a new instrument for screening dementia, the Cross Cultural Cognitive Examination (CCCE), is described. DESIGN: Criterion and concurrent validation and cross-cultural comparison of a new instrument. PARTICIPANTS: All individuals over the age of 40 in a village in southern Guam participated in a door-to-door survey. Alzheimer's and Parkinson's Disease patients and healthy controls aged 40-90 participated in the US mainland study. MEASUREMENTS: The CCCE was administered to all subjects. Effects of age, language, education, and gender on test performances and social-cultural differences were assessed. Concurrent validation of the test with respect to other well accepted screening instruments was determined. RESULTS: High specificity (> 94%) and sensitivity (> 99%) for detecting dementia were found in Guam and US mainland samples, and these were not biased by differences in gender, linguistic preference, education, or cultural background. Sensitivity and specificity of the CCCE matched or exceeded that of already accepted dementia screening instruments. CONCLUSIONS: These validation studies support the usefulness of the CCCE for identifying patients with generalized dementia, rather than focal types of cognitive impairment, quickly and reliably in cross-cultural neuroepidemiological research.
OBJECTIVE: Validation of a new instrument for screening dementia, the Cross Cultural Cognitive Examination (CCCE), is described. DESIGN: Criterion and concurrent validation and cross-cultural comparison of a new instrument. PARTICIPANTS: All individuals over the age of 40 in a village in southern Guam participated in a door-to-door survey. Alzheimer's and Parkinson's Diseasepatients and healthy controls aged 40-90 participated in the US mainland study. MEASUREMENTS: The CCCE was administered to all subjects. Effects of age, language, education, and gender on test performances and social-cultural differences were assessed. Concurrent validation of the test with respect to other well accepted screening instruments was determined. RESULTS: High specificity (> 94%) and sensitivity (> 99%) for detecting dementia were found in Guam and US mainland samples, and these were not biased by differences in gender, linguistic preference, education, or cultural background. Sensitivity and specificity of the CCCE matched or exceeded that of already accepted dementia screening instruments. CONCLUSIONS: These validation studies support the usefulness of the CCCE for identifying patients with generalized dementia, rather than focal types of cognitive impairment, quickly and reliably in cross-cultural neuroepidemiological research.
Authors: Nadia Sourial; Howard Bergman; Sathya Karunananthan; Christina Wolfson; Jack Guralnik; Hélène Payette; Luis Gutierrez-Robledo; Dorly J H Deeg; John D Fletcher; Maria T E Puts; Bin Zhu; François Béland Journal: J Gerontol A Biol Sci Med Sci Date: 2012-03-28 Impact factor: 6.053
Authors: Luis García-Fabela; Efrén Melano-Carranza; Sara Aguilar-Navarro; Juan Miguel Antonio García-Lara; Luis Miguel Gutiérrez-Robledo; José Alberto Avila-Funes Journal: Rev Invest Clin Date: 2009 Jul-Aug Impact factor: 1.451
Authors: Jianzhao Shen; Sujuan Gao; Frederick W Unverzagt; Adesola Ogunniyi; Olusegun Baiyewu; Oye Gureje; Hugh C Hendrie; Kathleen S Hall Journal: Int J Geriatr Psychiatry Date: 2006-07 Impact factor: 3.485