| Literature DB >> 8407109 |
K C Pugh1, L Gera, J M Stewart.
Abstract
3-Nitro-2-pyridinesulfenyl chloride (NpysCl) is the starting material for the synthesis of N-, O- and S-Npys-protected amino acids. Two efficient, novel synthetic routes to NpysCl are described. The stability of NpysCl was determined in a variety of solvents, with and without base, to determine the most suitable solvent and base for the synthesis of N-Npys amino acids. The syntheses of Npys-Ala and Boc-Lys(Npys) tert-butylammonium salt are also described.Entities:
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Year: 1993 PMID： 8407109 DOI： 10.1111/j.1399-3011.1993.tb00492.x
Source DB: PubMed Journal: Int J Pept Protein Res ISSN： 0367-8377